Literature DB >> 33300887

Multiple testing: when is many too much?

Rolf H H Groenwold1,2, Jelle J Goeman2, Saskia Le Cessie1,2, Olaf M Dekkers1,3.   

Abstract

In almost all medical research, more than a single hypothesis is being tested or more than a single relation is being estimated. Testing multiple hypotheses increases the risk of drawing a false-positive conclusion. We briefly discuss this phenomenon, which is often called multiple testing. Also, methods to mitigate the risk of false-positive conclusions are discussed.

Mesh：

Year:  2021        PMID： 33300887     DOI： 10.1530/EJE-20-1375

Source DB:  PubMed          Journal:  Eur J Endocrinol        ISSN： 0804-4643            Impact factor:   6.664


  7 in total

1.  Adherence to the healthy lifestyle guideline in relation to the metabolic syndrome: Analyses from the 2013 and 2018 Indonesian national health surveys.

Authors:  Fathimah S Sigit; Stella Trompet; Dicky L Tahapary; Dante S Harbuwono; Saskia le Cessie; Frits R Rosendaal; Renée de Mutsert
Journal:  Prev Med Rep       Date:  2022-04-27

Review 2.  Exploratory analyses in aetiologic research and considerations for assessment of credibility: mini-review of literature.

Authors:  Kim Luijken; Olaf M Dekkers; Frits R Rosendaal; Rolf H H Groenwold
Journal:  BMJ       Date:  2022-05-03

3.  Mobile Text Messaging for Tobacco Risk Communication Among Young Adult Community College Students: Randomized Trial of Project Debunk.

Authors:  Alexander V Prokhorov; Georges Elias Khalil; Karen Sue Calabro; Ashish Arya; Sophia Russell; Katarzyna W Czerniak; Gabrielle C Botello; Minxing Chen; Ying Yuan; Adriana Perez; Damon J Vidrine; Cheryl L Perry
Journal:  JMIR Mhealth Uhealth       Date:  2021-11-24       Impact factor: 4.773

4.  Altered gene expression profiles impair the nervous system development in individuals with 15q13.3 microdeletion.

Authors:  Marek B Körner; Akhil Velluva; Linnaeus Bundalian; Maximilian Radtke; Chen-Ching Lin; Pia Zacher; Tobias Bartolomaeus; Anna S Kirstein; Achmed Mrestani; Nicole Scholz; Konrad Platzer; Anne-Christin Teichmann; Julia Hentschel; Tobias Langenhan; Johannes R Lemke; Antje Garten; Rami Abou Jamra; Diana Le Duc
Journal:  Sci Rep       Date:  2022-08-05       Impact factor: 4.996

5.  Quantitative Analysis by 3D Graphics of Thoraco-Abdominal Surface Shape and Breathing Motion.

Authors:  Andrea Aliverti; Davide Lacca; Antonella LoMauro
Journal:  Front Bioeng Biotechnol       Date:  2022-07-13

6.  Association Between Vascular Overload Index and New-Onset Ischemic Stroke in Elderly Population with Hypertension.

Authors:  Yuling Yu; Yuqing Huang; Lin Liu; Xiao-Cong Liu; Qiuhong Tan; Chaolei Chen; Jiayi Huang; Yingqing Feng; Songtao Tang
Journal:  Clin Interv Aging       Date:  2021-07-08       Impact factor: 4.458

7.  Effects of exercise in breast cancer patients: implications of the trials within cohorts (TwiCs) design in the UMBRELLA Fit trial.

Authors:  Roxanne Gal; Evelyn M Monninkhof; Carla H van Gils; Rolf H H Groenwold; Sjoerd G Elias; Desirée H J G van den Bongard; Petra H M Peeters; Helena M Verkooijen; Anne M May
Journal:  Breast Cancer Res Treat       Date:  2021-08-24       Impact factor: 4.872
  7 in total

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