Literature DB >> 33299164

Hit movie reveals how a tuberculosis drug halts ATP synthesis.

Valerie Mizrahi, Clifton E Barry Iii.   

Abstract

Entities:  

Keywords:  Microbiology; Structural biology

Mesh:

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Year:  2021        PMID: 33299164     DOI: 10.1038/d41586-020-03406-x

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


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  11 in total

1.  ATP synthase in slow- and fast-growing mycobacteria is active in ATP synthesis and blocked in ATP hydrolysis direction.

Authors:  Anna C Haagsma; Nicole N Driessen; Marc-Manuel Hahn; Holger Lill; Dirk Bald
Journal:  FEMS Microbiol Lett       Date:  2010-10-07       Impact factor: 2.742

2.  A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis.

Authors:  Koen Andries; Peter Verhasselt; Jerome Guillemont; Hinrich W H Göhlmann; Jean-Marc Neefs; Hans Winkler; Jef Van Gestel; Philip Timmerman; Min Zhu; Ennis Lee; Peter Williams; Didier de Chaffoy; Emma Huitric; Sven Hoffner; Emmanuelle Cambau; Chantal Truffot-Pernot; Nacer Lounis; Vincent Jarlier
Journal:  Science       Date:  2004-12-09       Impact factor: 47.728

Review 3.  Structure and Mechanisms of F-Type ATP Synthases.

Authors:  Werner Kühlbrandt
Journal:  Annu Rev Biochem       Date:  2019-03-22       Impact factor: 23.643

4.  Treatment of Highly Drug-Resistant Pulmonary Tuberculosis.

Authors:  Francesca Conradie; Andreas H Diacon; Nosipho Ngubane; Pauline Howell; Daniel Everitt; Angela M Crook; Carl M Mendel; Erica Egizi; Joanna Moreira; Juliano Timm; Timothy D McHugh; Genevieve H Wills; Anna Bateson; Robert Hunt; Christo Van Niekerk; Mengchun Li; Morounfolu Olugbosi; Melvin Spigelman
Journal:  N Engl J Med       Date:  2020-03-05       Impact factor: 91.245

Review 5.  ATP synthase in mycobacteria: special features and implications for a function as drug target.

Authors:  Ping Lu; Holger Lill; Dirk Bald
Journal:  Biochim Biophys Acta       Date:  2014-02-07

6.  The uniqueness of subunit α of mycobacterial F-ATP synthases: An evolutionary variant for niche adaptation.

Authors:  Priya Ragunathan; Hendrik Sielaff; Lavanya Sundararaman; Goran Biuković; Malathy Sony Subramanian Manimekalai; Dhirendra Singh; Subhashri Kundu; Thorsten Wohland; Wayne Frasch; Thomas Dick; Gerhard Grüber
Journal:  J Biol Chem       Date:  2017-05-11       Impact factor: 5.157

7.  Diarylquinolines target subunit c of mycobacterial ATP synthase.

Authors:  Anil Koul; Najoua Dendouga; Karen Vergauwen; Brenda Molenberghs; Luc Vranckx; Rudy Willebrords; Zorica Ristic; Holger Lill; Ismet Dorange; Jerome Guillemont; Dirk Bald; Koen Andries
Journal:  Nat Chem Biol       Date:  2007-05-13       Impact factor: 15.040

8.  The structure of the catalytic domain of the ATP synthase from Mycobacterium smegmatis is a target for developing antitubercular drugs.

Authors:  Alice Tianbu Zhang; Martin G Montgomery; Andrew G W Leslie; Gregory M Cook; John E Walker
Journal:  Proc Natl Acad Sci U S A       Date:  2019-01-25       Impact factor: 11.205

9.  Effect of bedaquiline on mortality in South African patients with drug-resistant tuberculosis: a retrospective cohort study.

Authors:  Kathryn Schnippel; Norbert Ndjeka; Gary Maartens; Graeme Meintjes; Iqbal Master; Nazir Ismail; Jennifer Hughes; Hannetjie Ferreira; Xavier Padanilam; Rodolfo Romero; Julian Te Riele; Francesca Conradie
Journal:  Lancet Respir Med       Date:  2018-07-11       Impact factor: 30.700

10.  Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of Vo complex.

Authors:  Soung-Hun Roh; Mrinal Shekhar; Grigore Pintilie; Christophe Chipot; Stephan Wilkens; Abhishek Singharoy; Wah Chiu
Journal:  Sci Adv       Date:  2020-10-07       Impact factor: 14.136

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