| Literature DB >> 33295763 |
Erina Niijima1, Tomomi Imai1, Hayate Suzuki1, Yuuki Fujimoto2, Osamu Kitagawa1.
Abstract
The reaction of various optically pure N-C axially chiral quinazolin-4-one derivatives with Lawesson's reagent proceeded without a marked decrease in optical purity to give optically active quinazoline-4-thione derivatives (93-99% ee) possessing a high rotational barrier in good yields.Entities:
Year: 2020 PMID： 33295763 DOI： 10.1021/acs.joc.0c02319
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354