Literature DB >> 3329531

A controlled trial of nebulized aminoglycoside and oral flucloxacillin versus placebo in the outpatient management of children with cystic fibrosis.

F Carswell1, C Ward, D A Cook, D C Speller.   

Abstract

Six children with cystic fibrosis who had persistently had Pseudomonas aeruginosa isolated from their respiratory tract, completed a double-blind cross-over comparison of oral flucloxacillin and nebulized aminoglycoside versus double placebo. The patients had higher FEV1 results at the end of the month of active treatment than after the month of placebo.

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Year:  1987        PMID: 3329531     DOI: 10.1016/0007-0971(87)90184-7

Source DB:  PubMed          Journal:  Br J Dis Chest        ISSN: 0007-0971


  17 in total

Review 1.  Cystic fibrosis, pathophysiological and clinical aspects.

Authors:  H J Neijens; M Sinaasappel; R de Groot; J C de Jongste; S E Overbeek
Journal:  Eur J Pediatr       Date:  1990-08       Impact factor: 3.183

Review 2.  Lung infections. 3. Pseudomonas aeruginosa and other related species.

Authors:  R Wilson; R B Dowling
Journal:  Thorax       Date:  1998-03       Impact factor: 9.139

3.  Treatments for preventing recurrence of infection with Pseudomonas aeruginosa in people with cystic fibrosis.

Authors:  Sally Palser; Sherie Smith; Edward F Nash; Arnav Agarwal; Alan R Smyth
Journal:  Cochrane Database Syst Rev       Date:  2019-12-17

4.  Eradication therapy for Burkholderia cepacia complex in people with cystic fibrosis.

Authors:  Kate H Regan; Jayesh Bhatt
Journal:  Cochrane Database Syst Rev       Date:  2019-04-18

Review 5.  Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis.

Authors:  Sherie Smith; Nicola J Rowbotham; Edward Charbek
Journal:  Cochrane Database Syst Rev       Date:  2022-08-01

Review 6.  Nebulized antibiotics in cystic fibrosis.

Authors:  Isabelle Sermet-Gaudelus; Yann Le Cocguic; Agnés Ferroni; Marlène Clairicia; Joel Barthe; Jan-Pierre Delaunay; Valentine Brousse; Gérard Lenoir
Journal:  Paediatr Drugs       Date:  2002       Impact factor: 3.022

7.  Nebulised antipseudomonal antibiotic therapy in cystic fibrosis: a meta-analysis of benefits and risks.

Authors:  S Mukhopadhyay; M Singh; J I Cater; S Ogston; M Franklin; R E Olver
Journal:  Thorax       Date:  1996-04       Impact factor: 9.139

Review 8.  Antibiotic treatment for Burkholderia cepacia complex in people with cystic fibrosis experiencing a pulmonary exacerbation.

Authors:  Alex Horsley; Andrew M Jones; Robert Lord
Journal:  Cochrane Database Syst Rev       Date:  2016-01-20

9.  Tobramycin administered by the TOBI(®) Podhaler(®) for persons with cystic fibrosis: a review.

Authors:  Donald R Vandevanter; David E Geller
Journal:  Med Devices (Auckl)       Date:  2011-09-20

Review 10.  Interventions for the eradication of meticillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis.

Authors:  David Kh Lo; Marianne S Muhlebach; Alan R Smyth
Journal:  Cochrane Database Syst Rev       Date:  2018-07-21
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