PURPOSE: Centre-distance multifocal contact lenses (MFCLs) for myopia control are thought to slow myopia progression by providing both clear foveal vision and myopic defocus. Characterising the power profile of lenses is important to understanding their possible effects on retinal defocus when worn. The power profiles of three commercially available MFCLs were determined. METHODS: Three centre-distance MFCL designs were studied: Biofinity Multifocal D +2.50 add (comfilcon A), Proclear Multifocal D +2.50 add (omafilcon A), and NaturalVue Multifocal (etafilcon A). Two lenses each in power from -1.00D to -6.00D in 1D steps were stored in ISO 18369-3:2017 standard phosphate buffered saline for 24 h. Optical power profiles were measured in a wet cell with the SHSOphthalmic profiler accounting for centre thickness and manufacturer-reported material refractive index. Sagittal power maps from the SHSOphthalmic were exported, and custom MATLAB code was used to generate power profiles by averaging along the vertical and horizontal meridians. One-way anova with Tukey's HSD post-hoc t-tests were used to analyse maximum add power by lens design. RESULTS: Plus power increased out from the lens centre for all three MFCLs. Power profiles of Biofinity D and Proclear D MFCLs show three distinct areas within the optic zone; the distance zone (from lens centre to about 1.6 mm radius), intermediate zone (about 1.6 mm radius to 2.1 mm) and near zone (about 2 mm radius to 4 mm). For NaturalVue MFCLs, plus power starts increasing almost immediately from the lens centre, reaching maximum measured mean plus power at a radius of 2.7 mm. From 2.7 mm to 3.0 mm, there was a decrease in plus power, which was then generally maintained out to the optic zone edge. Across all lens powers, maximum add power was highest with the NaturalVue MFCL (+3.32 ± 0.44D), then Proclear D (+1.84 ± 0.28D) and Biofinity D (+1.47 ± 0.34D) MFCLs (all p < 0.04). Add power peaked at different locations for different lens powers and designs. CONCLUSIONS: Power profiles of MFCLs vary based on lens design and power. These power profiles are consistent with reported myopic and hyperopic changes in peripheral refraction with MFCLs and provide some explanation for reported differences in peripheral refraction with these MFCLs. Further work is needed to determine whether these power profile differences influence myopia progression.
PURPOSE: Centre-distance multifocal contact lenses (MFCLs) for myopia control are thought to slow myopia progression by providing both clear foveal vision and myopic defocus. Characterising the power profile of lenses is important to understanding their possible effects on retinal defocus when worn. The power profiles of three commercially available MFCLs were determined. METHODS: Three centre-distance MFCL designs were studied: Biofinity Multifocal D +2.50 add (comfilcon A), Proclear Multifocal D +2.50 add (omafilcon A), and NaturalVue Multifocal (etafilcon A). Two lenses each in power from -1.00D to -6.00D in 1D steps were stored in ISO 18369-3:2017 standard phosphate buffered saline for 24 h. Optical power profiles were measured in a wet cell with the SHSOphthalmic profiler accounting for centre thickness and manufacturer-reported material refractive index. Sagittal power maps from the SHSOphthalmic were exported, and custom MATLAB code was used to generate power profiles by averaging along the vertical and horizontal meridians. One-way anova with Tukey's HSD post-hoc t-tests were used to analyse maximum add power by lens design. RESULTS: Plus power increased out from the lens centre for all three MFCLs. Power profiles of Biofinity D and Proclear D MFCLs show three distinct areas within the optic zone; the distance zone (from lens centre to about 1.6 mm radius), intermediate zone (about 1.6 mm radius to 2.1 mm) and near zone (about 2 mm radius to 4 mm). For NaturalVue MFCLs, plus power starts increasing almost immediately from the lens centre, reaching maximum measured mean plus power at a radius of 2.7 mm. From 2.7 mm to 3.0 mm, there was a decrease in plus power, which was then generally maintained out to the optic zone edge. Across all lens powers, maximum add power was highest with the NaturalVue MFCL (+3.32 ± 0.44D), then Proclear D (+1.84 ± 0.28D) and Biofinity D (+1.47 ± 0.34D) MFCLs (all p < 0.04). Add power peaked at different locations for different lens powers and designs. CONCLUSIONS: Power profiles of MFCLs vary based on lens design and power. These power profiles are consistent with reported myopic and hyperopic changes in peripheral refraction with MFCLs and provide some explanation for reported differences in peripheral refraction with these MFCLs. Further work is needed to determine whether these power profile differences influence myopia progression.
Authors: Augustine N Nti; Hannah R Gregory; Eric R Ritchey; James S Wolffsohn; David A Berntsen Journal: Optom Vis Sci Date: 2022-04-01 Impact factor: 2.106