Literature DB >> 3329332

The production of heartwater vaccine.

P T Oberem1, J D Bezuidenhout.   

Abstract

The events leading to the production of an effective vaccine against heartwater are summarized. The production techniques used at Onderstepoort to produce and control the quality of the infected blood and nymph suspension vaccines, and covering their respective advantages and disadvantages, are compared. The many problems of these vaccines and how they may be overcome are discussed.

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Year:  1987        PMID： 3329332

Source DB:  PubMed          Journal:  Onderstepoort J Vet Res        ISSN： 0030-2465            Impact factor:   1.792


  8 in total

1.  Growth of Cowdria ruminantium, the causative agent of heartwater, in a tick cell line.

Authors:  L Bell-Sakyi; E A Paxton; U G Munderloh; K J Sumption
Journal:  J Clin Microbiol       Date:  2000-03       Impact factor: 5.948

2.  Monoclonal antibody binding to a surface-exposed epitope on Cowdria ruminantium that is conserved among eight strains.

Authors:  S Shompole; F R Rurangirwa; A Wambugu; J Sitienei; D M Mwangi; A J Musoke; S Mahan; C W Wells; T C McGuire
Journal:  Clin Diagn Lab Immunol       Date:  2000-11

3.  Identification of Cowdria ruminantium antigens that stimulate proliferation of lymphocytes from cattle immunized by infection and treatment or with inactivated organisms.

Authors:  M Van Kleef; N J Gunter; H Macmillan; B A Allsopp; V Shkap; W C Brown
Journal:  Infect Immun       Date:  2000-02       Impact factor: 3.441

4.  The genome of the heartwater agent Ehrlichia ruminantium contains multiple tandem repeats of actively variable copy number.

Authors:  Nicola E Collins; Junita Liebenberg; Etienne P de Villiers; Kelly A Brayton; Elmarié Louw; Alri Pretorius; F Erika Faber; Henriette van Heerden; Antoinette Josemans; Mirinda van Kleef; Helena C Steyn; M Fransie van Strijp; Erich Zweygarth; Frans Jongejan; Jean Charles Maillard; David Berthier; Marli Botha; Fourie Joubert; Craig H Corton; Nicholas R Thomson; Maria T Allsopp; Basil A Allsopp
Journal:  Proc Natl Acad Sci U S A       Date:  2005-01-06       Impact factor: 11.205

5.  Restriction of major surface protein 2 (MSP2) variants during tick transmission of the ehrlichia Anaplasma marginale.

Authors:  F R Rurangirwa; D Stiller; D M French; G H Palmer
Journal:  Proc Natl Acad Sci U S A       Date:  1999-03-16       Impact factor: 11.205

6.  Production of alpha interferon in Cowdria ruminantium-infected cattle and its effect on infected endothelial cell cultures.

Authors:  P Totté; F Jongejan; A L de Gee; J Wérenne
Journal:  Infect Immun       Date:  1994-06       Impact factor: 3.441

7.  Development and evaluation of PCR assay for detection of low levels of Cowdria ruminantium infection in Amblyomma ticks not detected by DNA probe.

Authors:  T F Peter; S L Deem; A F Barbet; R A Norval; B H Simbi; P J Kelly; S M Mahan
Journal:  J Clin Microbiol       Date:  1995-01       Impact factor: 5.948

8.  Protective immunity to heartwater (Cowdria ruminantium infection) is acquired after vaccination with in vitro-attenuated rickettsiae.

Authors:  F Jongejan
Journal:  Infect Immun       Date:  1991-02       Impact factor: 3.441
  8 in total

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