Literature DB >> 33284418

Umbilical cord medication in healthy full-term newborns: a before-after uncontrolled quality improvement study.

Alessandra Coscia1, Giovanni Boscarino2, Maria Di Chiara3, Francesca Faccioli3, Roberto Pedicino3, Elisa Onestà3, Antonella Giancotti3, Violante Di Donato3, Benedetta Ronchi3, Francesca Zantonelli3, Alessia Russo3, Chiara Mezzapiastra3, Gianluca Terrin3.   

Abstract

Umbilical cord care can be a stressful practice for parents. Complications of cord care can increase neonatal morbidity and mortality. The extracts of Arnica montana (AM) have been reported to possess antibacterial, anti-inflammatory, antifungal, and immunomodulatory activities. We aim to demonstrate the efficacy of AM on cord detachment and parents' stress level induced by cord medication in healthy full-term newborns. We enrolled full-term infants with a birth weight ≥ 2500 g in healthy conditions. Cord stumps of infants in the PRE-group were cleaned and dried, while cord stumps of infants in the POST-group were cleaned, dried, and medicated with a natural topic dermo-protective powder containing AM. After discharge, we interviewed parents on the stump status during follow-up visits in a pediatric office at 7 and 14 days of life, or by phone calls after follow-up visits. Long-rank test showed that time of cord separation of newborns in the PRE-group was significantly higher compared to that in the POST-group (p < 0.001). Parents of newborns in the PRE-group were significantly more stressed during cord medication compared to parents in the POST-group (2.0 (1.2 to 2.1) vs 1.0 (0.8 to 1.3), p = 0.011). Multivariate analysis showed a significantly linear relation with group assignment for cord separation (p < 0.001) and parents' stress during the medication (p = 0.033).
Conclusion: The use of a natural topic dermo-protective powder containing AM reduces the time of cord separation, improves parents' stress level, and reduces the risk of complications. What is Known: • Cord stump care can be a stressful practice for parents. • Antiseptic treatment recommended for cord care could be associated with side effects such as burning and sensitization. What is New: • The medication of cord stump with a natural topic dermo-protective powder containing Arnica montana reduces time of cord detachment and of complication such as redness', bleeding, or secretions. • The use of Arnica montana for cord medication may have a positive impact on the family, reducing parents' stress, and the use of other medications.

Entities:  

Keywords:  Arnica montana; Complications; Cord detachment; Cord stump; Newborns; Omphalitis; Parents’ stress

Mesh:

Substances:

Year:  2020        PMID: 33284418      PMCID: PMC7813727          DOI: 10.1007/s00431-020-03889-w

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  17 in total

1.  Umbilical cord care: the effect of eight different cord-care regimens on cord separation time and other outcomes.

Authors:  Marco Pezzati; Elena Cosenza Biagioli; Elena Martelli; Beatrice Gambi; Roberto Biagiotti; Firmino F Rubaltelli
Journal:  Biol Neonate       Date:  2002-01

2.  Efficacy of Arnica Echinacea powder in umbilical cord care in a large cohort study.

Authors:  Serafina Perrone; Silvia Coppi; Caterina Coviello; Sara Cecchi; Elisa Becucci; Maria Luisa Tataranno; Giuseppe Buonocore
Journal:  J Matern Fetal Neonatal Med       Date:  2012-04-24

3.  Uncontrolled before-after studies: discouraged by Cochrane and the EMJ.

Authors:  Steve Goodacre
Journal:  Emerg Med J       Date:  2015-03-27       Impact factor: 2.740

Review 4.  Umbilical Cord Care in the Newborn Infant.

Authors:  Dan Stewart; William Benitz
Journal:  Pediatrics       Date:  2016-09       Impact factor: 7.124

5.  Alcohol or traditional methods versus natural drying for newborn's cord care.

Authors:  Fatma Mohamed Nasr El-din Shoaeib; Sohair Abu El-Fadle Abdel All; Mohamed Abbas El-Barrawy
Journal:  J Egypt Public Health Assoc       Date:  2005

6.  Higher rate of cord-related adverse events in neonates with dry umbilical cord care compared to chlorhexidine powder. Results of a randomized controlled study to compare efficacy and safety of chlorhexidine powder versus dry care in umbilical cord care of the newborn.

Authors:  Thomas M Kapellen; Corinna M Gebauer; Oana Brosteanu; Birgit Labitzke; Christoph Vogtmann; Wieland Kiess
Journal:  Neonatology       Date:  2009-02-07       Impact factor: 4.035

7.  Immunologically active polysaccharides of Arnica montana cell cultures.

Authors:  J Puhlmann; M H Zenk; H Wagner
Journal:  Phytochemistry       Date:  1991       Impact factor: 4.072

8.  Umbilical cord separation time, predictors and healing complications in newborns with dry care.

Authors:  María Dolores López-Medina; Ana Belén López-Araque; Manuel Linares-Abad; Isabel María López-Medina
Journal:  PLoS One       Date:  2020-01-10       Impact factor: 3.240

9.  Antimicrobial Properties of MgO Nanostructures on Magnesium Substrates.

Authors:  Jiajia Lin; Nhu-Y Thi Nguyen; Chaoxing Zhang; Alexandra Ha; Huinan Hannah Liu
Journal:  ACS Omega       Date:  2020-09-18

10.  Green Synthesis of Zinc Oxide Nanoparticles from Pomegranate (Punica granatum) Extracts and Characterization of Their Antibacterial Activity.

Authors:  Ugochi Lydia Ifeanyichukwu; Omolola Esther Fayemi; Collins Njie Ateba
Journal:  Molecules       Date:  2020-10-02       Impact factor: 4.411

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