Literature DB >> 33282101

A Case of Vancomycin-induced Acute Generalized Exanthematous Pustulosis Confirmed by Patch Testing.

Cory Pettit1, John Trinidad1, Benjamin Kaffenberger1.   

Abstract

Acute generalized exanthematous pustulosis (AGEP) is a rare cutaneous drug reaction that presents with the rapid onset of disseminated pustules, erythema, and edema. It is commonly associated with pristinamycin and aminopenicillins, but a few cases of vancomycin induced AGEP have been reported. Here, we describe a patient who presented with AGEP 12 hours following vancomycin administration, and had an atypical clinical course, with the AGEP persisting for weeks. Vancomycin was confirmed to be the etiologic agent with patch testing, a modality with growing evidence for utility in drug-induced reaction cases.
Copyright © 2020. Matrix Medical Communications. All rights reserved.

Entities:  

Keywords:  Vancomycin; acute generalized exanthematous pustulosis; cutaneous drug reaction

Year:  2020        PMID： 33282101      PMCID： PMC7716735     

Source DB:  PubMed          Journal:  J Clin Aesthet Dermatol        ISSN： 1941-2789


  9 in total

1.  Acute generalised exanthematous pustulosis mimicking septic shock.

Authors:  W Joost Lesterhuis; Milan Tjioe; Georg A Stumpenhausen; Reinout van Crevel
Journal:  Am J Med       Date:  2004-04-15       Impact factor: 4.965

2.  Acute generalized exanthematous pustulosis: clinical characteristics, etiologic associations, treatments, and outcomes in a series of 28 patients at Mayo Clinic, 1996-2013.

Authors:  Dema T Alniemi; David A Wetter; Alina G Bridges; Rokea A El-Azhary; Mark D P Davis; Michael J Camilleri; Marian T McEvoy
Journal:  Int J Dermatol       Date:  2017-01-13       Impact factor: 2.736

3.  A multicentre study to determine the value and safety of drug patch tests for the three main classes of severe cutaneous adverse drug reactions.

Authors:  A Barbaud; E Collet; B Milpied; H Assier; D Staumont; M Avenel-Audran; A Grange; S Amarger; P Girardin; M-T Guinnepain; F Truchetet; A Lasek; J Waton
Journal:  Br J Dermatol       Date:  2013-03       Impact factor: 9.302

4.  A pentad of vancomycin reactions.

Authors:  Meghan O'Brien; Avnee Shah; Herbert B Allen
Journal:  Skinmed       Date:  2011 Jul-Aug

5.  Patch testing - a valuable tool for investigating non-immediate cutaneous adverse drug reactions to antibiotics.

Authors:  A Pinho; I Coutinho; A Gameiro; M Gouveia; M Gonçalo
Journal:  J Eur Acad Dermatol Venereol       Date:  2016-08-01       Impact factor: 6.166

6.  Acute generalized exanthematous pustulosis with multiple organ dysfunction syndrome.

Authors:  Ghulam Rehman Mohyuddin; Manar Al Asad; Lindsay Scratchko; Ghulam Khaleeq
Journal:  Am J Crit Care       Date:  2013-05       Impact factor: 2.228

Review 7.  Acute generalised exanthematous pustulosis.

Authors:  Suran L Fernando
Journal:  Australas J Dermatol       Date:  2011-12-29       Impact factor: 2.875

Review 8.  Acute Generalized Exanthematous Pustulosis: Pathogenesis, Genetic Background, Clinical Variants and Therapy.

Authors:  Laurence Feldmeyer; Kristine Heidemeyer; Nikhil Yawalkar
Journal:  Int J Mol Sci       Date:  2016-07-27       Impact factor: 5.923

9.  Vancomycin-induced acute generalized exanthematous pustulosis (AGEP) masquerading septic shock-an unusual presentation of a rare disease.

Authors:  Sagger Mawri; Tarun Jain; Jainil Shah; Gina Hurst; Jennifer Swiderek
Journal:  J Intensive Care       Date:  2015-11-10
  9 in total
  1 in total

Review 1.  Drug Triggers and Clinic of Acute Generalized Exanthematous Pustulosis (AGEP): A Literature Case Series of 297 Patients.

Authors:  Enriqueta Vallejo-Yagüe; Adrian Martinez-De la Torre; Omar S Mohamad; Shweta Sabu; Andrea M Burden
Journal:  J Clin Med       Date:  2022-01-13       Impact factor: 4.241
  1 in total

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