Annick Vogels1,2, Gilles Droogmans3, Elfi Vergaelen4, Griet Van Buggenhout1,2, Ann Swillen1,2. 1. Center for Human Genetics, University Hospital Gasthuisberg. 2. Department of Human Genetics. 3. Research Unit for Parenting and Special Education. 4. University Psychiatric Center, Mind Body Research Group, KU Leuven (University of Leuven), Leuven, Belgium.
Abstract
PURPOSE OF REVIEW: The purpose of this review is to summarize the literature on cognitive development, communication, behavioral or psychiatric aspects in Phelan-McDermid syndrome (PMS) and to discuss the clinical implications and recommendations of these summarized findings. RECENT FINDINGS: PMS is often associated with severe communication impairments, behavioral or psychiatric problems and regression. These challenges may adversely affect and impair the quality of life of the individual with PMS and his family. SUMMARY: Individuals with PMS experience intellectual disability, communication and behavioral/psychiatric challenges, such as catatonia, bipolar disorder and regression across the lifespan. Providing appropriate guidance and support to them and their families demands a better understanding of these challenges.
PURPOSE OF REVIEW: The purpose of this review is to summarize the literature on cognitive development, communication, behavioral or psychiatric aspects in Phelan-McDermid syndrome (PMS) and to discuss the clinical implications and recommendations of these summarized findings. RECENT FINDINGS: PMS is often associated with severe communication impairments, behavioral or psychiatric problems and regression. These challenges may adversely affect and impair the quality of life of the individual with PMS and his family. SUMMARY: Individuals with PMS experience intellectual disability, communication and behavioral/psychiatric challenges, such as catatonia, bipolar disorder and regression across the lifespan. Providing appropriate guidance and support to them and their families demands a better understanding of these challenges.
Authors: Annemiek M Landlust; Linda Visser; Boudien C T Flapper; Selma A J Ruiter; Renée J Zwanenburg; Conny M A van Ravenswaaij-Arts; Ingrid D C van Balkom Journal: Front Psychiatry Date: 2022-05-26 Impact factor: 5.435
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