Literature DB >> 3327607

The RAD50 gene of Saccharomyces cerevisiae is not essential for vegetative growth.

M Kupiec1.   

Abstract

The gene RAD50 was located by the ability of subclones to restore the Rad+ phenotype following transformation of a rad50-1 mutant. Disruption of the gene was achieved by directed integration of a plasmid carrying a fragment internal to RAD50. Haploids with the disrupted gene are viable and do not differ in growth rate or plating efficiency from isogenic rad50-1 or Rad+ strains.

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Year:  1986        PMID： 3327607     DOI： 10.1007/bf00419878

Source DB:  PubMed          Journal:  Curr Genet        ISSN： 0172-8083            Impact factor:   3.886


  13 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Cloning and integrative deletion of the RAD6 gene of Saccharomyces cerevisiae.

Authors:  M Kupiec; G Simchen
Journal:  Curr Genet       Date:  1984-10       Impact factor: 3.886

3.  Replacement of chromosome segments with altered DNA sequences constructed in vitro.

Authors:  S Scherer; R W Davis
Journal:  Proc Natl Acad Sci U S A       Date:  1979-10       Impact factor: 11.205

4.  Repair systems in Saccharomyces.

Authors:  B Cox; J Game
Journal:  Mutat Res       Date:  1974-08       Impact factor: 2.433

5.  A genetic study of x-ray sensitive mutants in yeast.

Authors:  J C Game; R K Mortimer
Journal:  Mutat Res       Date:  1974-09       Impact factor: 2.433

6.  The Role of Radiation (rad) Genes in Meiotic Recombination in Yeast.

Authors:  J C Game; T J Zamb; R J Braun; M Resnick; R M Roth
Journal:  Genetics       Date:  1980-01       Impact factor: 4.562

7.  Recombinationless meiosis in Saccharomyces cerevisiae.

Authors:  R E Malone; R E Esposito
Journal:  Mol Cell Biol       Date:  1981-10       Impact factor: 4.272

8.  Cloning and mapping of the RAD50 gene of Saccharomyces cerevisiae.

Authors:  M Kupiec; G Simchen
Journal:  Mol Gen Genet       Date:  1984

9.  RAD3 gene of Saccharomyces cerevisiae: nucleotide sequence of wild-type and mutant alleles, transcript mapping, and aspects of gene regulation.

Authors:  L Naumovski; G Chu; P Berg; E C Friedberg
Journal:  Mol Cell Biol       Date:  1985-01       Impact factor: 4.272

10.  Extragenic revertants of rad50, a yeast mutation causing defects in recombination and repair.

Authors:  R E Malone; K Jordan; W Wardman
Journal:  Curr Genet       Date:  1985       Impact factor: 3.886
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  2 in total

1.  Expression of the Saccharomyces cerevisiae RAD50 gene during meiosis: steady-state transcript levels rise and fall while steady-state protein levels remain constant.

Authors:  W E Raymond; N Kleckner
Journal:  Mol Gen Genet       Date:  1993-04

Review 2.  Deoxyribonucleic acid repair in the yeast Saccharomyces cerevisiae.

Authors:  E C Friedberg
Journal:  Microbiol Rev       Date:  1988-03
  2 in total

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