| Literature DB >> 33275886 |
Warren L Wu1, Thales Papagiannakopoulos2.
Abstract
Takahashi et al. (2020) conduct a focused CRISPR/Cas9 screen against NRF2 target and other redox regulatory genes in both 2D- and 3D-culture systems, uncovering a vulnerability of spheroid cancer cells deprived of extracellular matrix to undergo ferroptosis.Entities:
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Year: 2020 PMID： 33275886 DOI： 10.1016/j.molcel.2020.11.022
Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 19.328