Significance of plasma amino acid pattern in preterm infants.

Nutritional studies frequently take into consideration plasma amino acid concentrations in order to evaluate the adequacy of protein intake in preterm infants. From our data of more than 100 determinations of plasma amino acid concentrations in preterm infants, we review the factors influencing the aminogram. Method and moment of sampling, protein intake and composition, protein turnover rate, energy supply, and gestational age, all may influence plasma amino acid concentrations. It is suggested that the cord blood amino acid concentration may be considered as an appropriate value of reference and a safe level for growing preterm infants.