Literature DB >> 33274651

Optimizing electronic capture of patient-reported outcome measures in oncology clinical trials: lessons learned from a qualitative study.

Florence D Mowlem1, Brad Sanderson1, Jill V Platko2, Bill Byrom1.   

Abstract

Aim: To understand the impact of anticancer treatment on oncology patients' ability to use electronic solutions for completing patient-reported outcomes (ePRO). Materials & methods: Semi-structured interviews were conducted with seven individuals who had experienced a cancer diagnosis and treatment.
Results:  Participants reported that the following would impact the ability to interact with an ePRO solution: peripheral neuropathy of the hands (4/7), fatigue and/or concentration and memory issues (6/7), where they are in a treatment cycle (5/7). Approaches to improve usability included: larger, well-spaced buttons to deal with finger numbness, the ability to pause a survey and complete at a later point and presenting the recall period with every question to reduce reliance on memory.
Conclusion: Symptoms associated with cancers and anticancer treatments can impact the use of technologies. The recommendations for optimizing the electronic implementation of patient-reported outcome instruments in this population provides the potential to improve data quality in oncology trials and places patient needs at the forefront to ensure 'fit-for-purpose' solutions.

Entities:  

Keywords:  clinical trials; eCOA; ePRO; ePROMs; oncology; patient-reported outcome measures; usability

Mesh:

Substances:

Year:  2020        PMID: 33274651     DOI: 10.2217/cer-2020-0143

Source DB:  PubMed          Journal:  J Comp Eff Res        ISSN: 2042-6305            Impact factor:   1.744


  2 in total

1.  What role can decentralized trial designs play to improve rare disease studies?

Authors:  J Moore; N Goodson; P Wicks; J Reites
Journal:  Orphanet J Rare Dis       Date:  2022-06-20       Impact factor: 4.303

2.  Regulatory Acceptance of Patient-Reported Outcome (PRO) Data from Bring-Your-Own-Device (BYOD) Solutions to Support Medical Product Labeling Claims : Let's Share the Success Stories to Move the Industry Forward.

Authors:  Florence D Mowlem; Pamela Tenaerts; Chad Gwaltney; Ingrid Oakley-Girvan
Journal:  Ther Innov Regul Sci       Date:  2022-05-09       Impact factor: 1.337

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.