Literature DB >> 33274521

Donor management using a specialized donor care facility is associated with higher organ utilization from drug overdose donors.

Christian Corbin Frye1, Jason M Gauthier1, Amit Bery2, William D Gerull1, Deniz B Morkan1, Jingxia Liu3, M Shea Harrison1, Yuriko Terada1, Judith E Van Zanden1, Gary F Marklin4, Michael K Pasque1, Ruben G Nava1, Bryan F Meyers1, Alexander G Patterson1, Benjamin D Kozower1, Ramsey Hachem3, Derek Byers3, Chad Witt3, Hrishikesh Kulkarni3, Daniel Kreisel1,5, Varun Puri1.   

Abstract

Drug overdoses have tripled in the United States over the last two decades. With the increasing demand for donor organs, one potential consequence of the opioid epidemic may be an increase in suitable donor organs. Unfortunately, organs from donors dying of drug overdose have poorer utilization rates than other groups of brain-dead donors, largely due to physician and recipient concerns about viral disease transmission. During the study period of 2011 to 2016, drug overdose donors (DODs) account for an increasingly greater proportion of the national donor pool. We show that a novel model of donor care, known as specialized donor care facility (SDCF), is associated with an increase in organ utilization from DODs compared to the conventional model of hospital-based donor care. This is likely related to the close relationship of the SDCF with the transplant centers, leading to improved communication and highly efficient donor care.
© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  Scientific Registry for Transplant Recipients; donors and donation; organ allocation

Mesh:

Substances:

Year:  2020        PMID: 33274521      PMCID: PMC8248520          DOI: 10.1111/ctr.14178

Source DB:  PubMed          Journal:  Clin Transplant        ISSN: 0902-0063            Impact factor:   2.863


  31 in total

1.  Operative start times and complications after liver transplantation.

Authors:  B E Lonze; A Parsikia; E L Feyssa; K Khanmoradi; V R Araya; R F Zaki; D L Segev; J A Ortiz
Journal:  Am J Transplant       Date:  2010-08       Impact factor: 8.086

2.  Improving Organ Utilization to Help Overcome the Tragedies of the Opioid Epidemic.

Authors:  D S Goldberg; E Blumberg; M McCauley; P Abt; M Levine
Journal:  Am J Transplant       Date:  2016-08-24       Impact factor: 8.086

3.  Centers for Disease Control 'high-risk' donors and kidney utilization.

Authors:  K I Duan; M J Englesbe; M L Volk
Journal:  Am J Transplant       Date:  2009-12-02       Impact factor: 8.086

4.  The Drug-Intoxication Epidemic and Solid-Organ Transplantation.

Authors:  Mandeep R Mehra; John A Jarcho; Wida Cherikh; Muthiah Vaduganathan; Rebecca R Lehman; Jacqueline Smits; Josef Stehlik
Journal:  N Engl J Med       Date:  2018-05-17       Impact factor: 91.245

5.  Personal experience and reputation interact in human decisions to help reciprocally.

Authors:  Lucas Molleman; Eva van den Broek; Martijn Egas
Journal:  Proc Biol Sci       Date:  2013-02-27       Impact factor: 5.349

6.  Organ Donor Recovery Performed at an Organ Procurement Organization-Based Facility Is an Effective Way to Minimize Organ Recovery Costs and Increase Organ Yield.

Authors:  Majella Doyle; Vijay Subramanian; Neeta Vachharajani; Kelly Collins; Jason R Wellen; Emily Stahlschmidt; Diane Brockmeier; Jason Coleman; Dean Kappel; William C Chapman
Journal:  J Am Coll Surg       Date:  2016-02-29       Impact factor: 6.113

7.  The Drug Overdose Epidemic and Deceased-Donor Transplantation in the United States: A National Registry Study.

Authors:  Christine M Durand; Mary G Bowring; Alvin G Thomas; Lauren M Kucirka; Allan B Massie; Andrew Cameron; Niraj M Desai; Mark Sulkowski; Dorry L Segev
Journal:  Ann Intern Med       Date:  2018-04-17       Impact factor: 25.391

8.  Surgical quality in organ procurement during day and night: an analysis of quality forms.

Authors:  Jacob de Boer; Koen Van der Bogt; Hein Putter; Kirsten Ooms-de Vries; Bernadette Haase-Kromwijk; Robert Pol; Jeroen De Jonge; Kees Dejong; Mijntje Nijboer; Daan Van der Vliet; Dries Braat
Journal:  BMJ Open       Date:  2018-11-25       Impact factor: 2.692

9.  Drug and Opioid-Involved Overdose Deaths - United States, 2013-2017.

Authors:  Lawrence Scholl; Puja Seth; Mbabazi Kariisa; Nana Wilson; Grant Baldwin
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2018-01-04       Impact factor: 17.586

10.  Racial/Ethnic and Age Group Differences in Opioid and Synthetic Opioid-Involved Overdose Deaths Among Adults Aged ≥18 Years in Metropolitan Areas - United States, 2015-2017.

Authors:  Kumiko M Lippold; Christopher M Jones; Emily O'Malley Olsen; Brett P Giroir
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2019-11-01       Impact factor: 17.586

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