Literature DB >> 332704

Analysis of biological and immunological activities in the two pools of LH released during constant infusion of luteinizing hormone-releasing hormone (LHRH) in men.

I Z Beitins, M L Dufau, K O'Loughlin, K J Catt, J W McArthur.   

Abstract

In response to constant infusion of a submaximal dose of LHRH (0.2 microgram/min for 4 hours), luteinizing hormone (LH) was released in a biphasic pattern in 6 normal men. When the in vitro biologic activity of plasma LH was compared to the immunologic activity throughout the response to LHRH, the B/I ratio remained unchanged (3.6 +/- 0.5, mean +/- SE). Thus, in men the biologic activity of stored LH (acutely releasable) is not different from the presumably newly synthesized hormone that is released as the second pool during prolonged LHRH infusion.

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Year:  1977        PMID: 332704     DOI: 10.1210/jcem-45-3-605

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN: 0021-972X            Impact factor:   5.958


  8 in total

1.  Age and sex related variations in biologically active and immunoreactive serum luteinizing hormone.

Authors:  P Marrama; A A Zaidi; V Montanini; M F Celani; K Cioni; C Carani; F Morabito; M Resentini; B Bonati; G F Baraghini
Journal:  J Endocrinol Invest       Date:  1983-12       Impact factor: 4.256

2.  Estradiol modulates the pulsatile secretion of biologically active luteinizing hormone in man.

Authors:  J D Veldhuis; M L Dufau
Journal:  J Clin Invest       Date:  1987-09       Impact factor: 14.808

3.  Attenuated release of biologically active luteinizing hormone in healthy aging men.

Authors:  R J Urban; J D Veldhuis; R M Blizzard; M L Dufau
Journal:  J Clin Invest       Date:  1988-04       Impact factor: 14.808

4.  Biological activity of luteinizing hormone in uraemic children: spontaneous nocturnal secretion and changes after administration of exogenous pulsatile luteinizing hormone-releasing hormone--preliminary observations.

Authors:  M Giusti; F Perfumo; E Verrina; D Cavallero; G Piaggio; R Gusmano; G Giordano
Journal:  Pediatr Nephrol       Date:  1991-07       Impact factor: 3.714

5.  Endogenous opiates modulate the pulsatile secretion of biologically active luteinizing hormone in man.

Authors:  J D Veldhuis; A D Rogol; M L Johnson
Journal:  J Clin Invest       Date:  1983-12       Impact factor: 14.808

6.  Delayed puberty in uremia: pituitary-gonadal function during short-term pulsatile luteinizing hormone-releasing hormone administration.

Authors:  M Giusti; F Perfumo; E Verrina; D Cavallero; G Piaggio; S Valenti; R Gusmano; G Giordano
Journal:  J Endocrinol Invest       Date:  1992-11       Impact factor: 4.256

7.  Naloxone increases bioactive LH in man: evidence for selective release of early LH pool.

Authors:  F Fraioli; A Fabbri; L Gnessi; C Moretti; V Bonifacio; A Isidori; M Dufau
Journal:  J Endocrinol Invest       Date:  1985-12       Impact factor: 4.256

8.  Effects of acute stimulation with gonadotropin releasing hormone (GnRH) on biologically active serum luteinizing hormone (LH) in elderly men.

Authors:  M F Celani; V Montanini; G F Baraghini; C Carani; P Marrama
Journal:  J Endocrinol Invest       Date:  1984-12       Impact factor: 4.256

  8 in total

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