Literature DB >> 33269895

Pelvic Fragility Fractures: An Opportunity to Improve the Undertreatment of Osteoporosis.

Christian T Smith1, David W Barton, Amit S Piple, Jonathan J Carmouche.   

Abstract

BACKGROUND: Osteoporosis is often undiagnosed until patients experience fragility fractures. Pelvic fractures are common but underappreciated sentinel fractures. Screening patients with a pelvic fracture for osteoporosis may provide an opportunity to initiate appropriate treatments such as anti-osteoporosis therapy to prevent additional fractures.
METHODS: This retrospective cohort review examined the management of osteoporosis after pelvic fractures at a large tertiary care center without an established secondary fracture prevention program. Data were extracted from electronic medical records of all new patients with a pelvic fracture who were ≥50 years of age from this center and its affiliated community hospitals from 2008 to 2014. Outcome measures included the initiation of anti-osteoporosis therapy before the fracture, within the year following the fracture, >1 year following the fracture, or never and new osteoporotic fractures within 2 years after a pelvic fracture.
RESULTS: From 2008 to 2014, 947 patients presented with pelvic fractures. Of these patients, 27.1% (257 patients) were taking anti-osteoporosis medications before the fracture. Four percent of treatment-naïve patients began anti-osteoporosis therapy within 1 year of fracture, with 1.2% (11 patients) starting after 1 year. Of the treatment-naïve patients, 92.3% (637 patients) were never prescribed anti-osteoporosis therapy. Treatment rates were consistent over time. Within 2 years, 41.0% (388 patients) developed fragility fractures at secondary sites: 12.0% (114 patients) experienced a hip fracture, and 16.4% (155 patients) experienced a vertebral fracture.
CONCLUSIONS: Osteoporosis screening and initiation of secondary fracture prevention after a pelvic fracture were inadequate in the study population. Of the patients in this study, 909 (96.0%) never underwent a dual x-ray absorptiometry (DXA) scan during the study period. Of the 690 treatment-naïve patients, 637 (92.3%) were never administered anti-osteoporosis medications. Within 2 years, 41.0% of all patients developed additional osteoporotic fractures. This study demonstrates an opportunity to improve bone health by screening for and treating osteoporosis in patients with a pelvic fragility fracture. LEVEL OF EVIDENCE: Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.

Entities:  

Year:  2020        PMID: 33269895     DOI: 10.2106/JBJS.20.00738

Source DB:  PubMed          Journal:  J Bone Joint Surg Am        ISSN: 0021-9355            Impact factor:   5.284


  5 in total

1.  Pelvic Fractures-An Underestimated Problem? Incidence and Mortality Risk after Pelvic Fracture in Austria, 2010-2018.

Authors:  Martina Behanova; Judith Haschka; Berthold Reichardt; Hans-Peter Dimai; Heinrich Resch; Jochen Zwerina; Roland Kocijan
Journal:  J Clin Med       Date:  2022-05-17       Impact factor: 4.964

2.  Teriparatide and pelvic fracture healing: a phase 2 randomized controlled trial.

Authors:  J W Nieves; F Cosman; D McMahon; M Redko; I Hentschel; R Bartolotta; M Loftus; J J Kazam; J Rotman; J Lane
Journal:  Osteoporos Int       Date:  2021-08-12       Impact factor: 4.507

3.  High prevalence of missed information related on bone health in orthogeriatric patients with fragility fractures of the pelvis-an institutional register-based analysis.

Authors:  J Gleich; A Cavalcanti Kußmaul; E Steiner; W Böcker; C Neuerburg; C Linhart
Journal:  Osteoporos Int       Date:  2021-11-24       Impact factor: 4.507

4.  The impact of specific fracture characteristics of low-energy fractures of the pelvis on mortality.

Authors:  Franziska Saxer; Henrik Eckardt; Michaela Ramser; Werner Vach; Nathalie Strub; Dieter Cadosch
Journal:  BMC Geriatr       Date:  2022-08-15       Impact factor: 4.070

5.  Inverse association between low-density lipoprotein cholesterol and bone mineral density in young- and middle-aged people: The NHANES 2011-2018.

Authors:  Fangjun Xiao; Peng Peng; Shihua Gao; Tianye Lin; Weihua Fang; Wei He
Journal:  Front Med (Lausanne)       Date:  2022-08-10
  5 in total

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