| Literature DB >> 33268959 |
Maryam Alkhatry1, Ahmad Al-Rifai2, Vito Annese3, Filippos Georgopoulos4, Ahmad N Jazzar5, Ahmed M Khassouan6, Zaher Koutoubi7, Rahul Nathwani8, Mazen S Taha9, Jimmy K Limdi10.
Abstract
Ulcerative colitis and Crohn's disease are the main entities of inflammatory bowel disease characterized by chronic remittent inflammation of the gastrointestinal tract. The incidence and prevalence are on the rise worldwide, and the heterogeneity between patients and within individuals over time is striking. The progressive advance in our understanding of the etiopathogenesis coupled with an unprecedented increase in therapeutic options have changed the management towards evidence-based interventions by clinicians with patients. This guideline was stimulated and supported by the Emirates Gastroenterology and Hepatology Society following a systematic review and a Delphi consensus process that provided evidence- and expert opinion-based recommendations. Comprehensive up-to-date guidance is provided regarding diagnosis, evaluation of disease severity, appropriate and timely use of different investigations, choice of appropriate therapy for induction and remission phase according to disease severity, and management of main complications. ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.Entities:
Keywords: Adalimumab; Crohn’s disease; Infliximab; Tofacitinib; Ulcerative colitis; Ustekinumab; Vedolizumab
Mesh:
Year: 2020 PMID: 33268959 PMCID: PMC7684461 DOI: 10.3748/wjg.v26.i43.6710
Source DB: PubMed Journal: World J Gastroenterol ISSN: 1007-9327 Impact factor: 5.742