Literature DB >> 3326527

In vitro activities of ICI 194008 and ICI 193428, two new cephem antimicrobial agents.

J D Allan1, G M Eliopoulos, E Reiszner, R C Moellering.   

Abstract

The in vitro activities of two new cephem antibiotics, ICI 193428 and ICI 194008, were compared with those of cefpirome, cefotaxime, ceftazidime, and piperacillin. Essentially all strains of the family Enterobacteriaceae were inhibited by both study drugs at concentrations of less than or equal to 4 micrograms/ml. Both new cephems were comparable to ceftazidime against Pseudomonas aeruginosa (MIC for 90% of strains, 8 micrograms/ml) and were the most active agents tested against Pseudomonas maltophilia (MIC for 90% of strains, 16 micrograms/ml).

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Year:  1987        PMID： 3326527      PMCID： PMC175842          DOI： 10.1128/AAC.31.12.1997

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

1.  Activity of beta-lactam antibiotics against Pseudomonas aeruginosa carrying R plasmids determining different beta-lactamases.

Authors:  G A Jacoby; L Sutton
Journal:  Antimicrob Agents Chemother       Date:  1979-08       Impact factor: 5.191

Review 2.  Classification of beta-lactamases.

Authors:  A Bauernfeind
Journal:  Rev Infect Dis       Date:  1986 Nov-Dec

Review 3.  The beta-lactamases of gram-negative bacteria and their role in resistance to beta-lactam antibiotics.

Authors:  R B Sykes; M Matthew
Journal:  J Antimicrob Chemother       Date:  1976-06       Impact factor: 5.790

4.  Purification and properties of an inducible cephalosporinase from Pseudomonas maltophilia GN12873.

Authors:  Y Saino; M Inoue; S Mitsuhashi
Journal:  Antimicrob Agents Chemother       Date:  1984-03       Impact factor: 5.191

5.  In-vitro activity of Sch 29482 in comparison with other oral antibiotics.

Authors:  G M Eliopoulos; A Gardella; R C Moellering
Journal:  J Antimicrob Chemother       Date:  1982-02       Impact factor: 5.790

6.  Method of reliable determination of minimal lethal antibiotic concentrations.

Authors:  R D Pearson; R T Steigbigel; H T Davis; S W Chapman
Journal:  Antimicrob Agents Chemother       Date:  1980-11       Impact factor: 5.191

7.  In vitro antagonism of beta-lactam antibiotics by cefoxitin.

Authors:  C C Sanders; W E Sanders; R V Goering
Journal:  Antimicrob Agents Chemother       Date:  1982-06       Impact factor: 5.191

8.  Multiply resistant viridans streptococci: susceptibility to beta-lactam antibiotics and comparison of penicillin-binding protein patterns.

Authors:  B F Farber; G M Eliopoulos; J I Ward; K L Ruoff; V Syriopoulou; R C Moellering
Journal:  Antimicrob Agents Chemother       Date:  1983-11       Impact factor: 5.191

9.  Comparative in vitro activities of cefpiramide and apalcillin individually and in combination.

Authors:  J D Allan; G M Eliopoulos; M J Ferraro; R C Moellering
Journal:  Antimicrob Agents Chemother       Date:  1985-05       Impact factor: 5.191

10.  Effects of azlocillin in combination with clavulanic acid, sulbactam, and N-formimidoyl thienamycin against beta-lactamase-producing, carbenicillin-resistant Pseudomonas aeruginosa.

Authors:  S B Calderwood; A Gardella; A M Philippon; G A Jacoby; R C Moellering
Journal:  Antimicrob Agents Chemother       Date:  1982-08       Impact factor: 5.191
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  2 in total

1.  Comparative in vitro activity of WIN 57273, a new fluoroquinolone antimicrobial agent.

Authors:  G M Eliopoulos; K Klimm; L B Rice; M J Ferraro; R C Moellering
Journal:  Antimicrob Agents Chemother       Date:  1990-06       Impact factor: 5.191

2.  In vitro activity of BAY v 3522, a new cephalosporin for oral administration.

Authors:  T L Hodges; G M Eliopoulos; K Klimm; R C Moellering
Journal:  Antimicrob Agents Chemother       Date:  1990-09       Impact factor: 5.191
  2 in total

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