Literature DB >> 33264600

Lipid Metabolism Gets in a JAML during Kidney Disease.

Alessia Fornoni1, Sandra Merscher2.   

Abstract

It is still unclear if the ability of key regulators of actin cytoskeletal remodeling to influence lipid metabolism contributes to kidney injury. In this issue of Cell Metabolism, Fu et al. (2020) show that junctional adhesion molecule-like (JAML) is a novel mediator of glomerular disease progression while suggesting a direct link between defects in cell adhesion and lipotoxicity.
Copyright © 2020 Elsevier Inc. All rights reserved.

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Year:  2020        PMID: 33264600      PMCID: PMC7978490          DOI: 10.1016/j.cmet.2020.11.002

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   27.287


  10 in total

1.  Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense.

Authors:  Marta Bosch; Miguel Sánchez-Álvarez; Alba Fajardo; Ronan Kapetanovic; Bernhard Steiner; Filipe Dutra; Luciana Moreira; Juan Antonio López; Rocío Campo; Montserrat Marí; Frederic Morales-Paytuví; Olivia Tort; Albert Gubern; Rachel M Templin; James E B Curson; Nick Martel; Cristina Català; Francisco Lozano; Francesc Tebar; Carlos Enrich; Jesús Vázquez; Miguel A Del Pozo; Matthew J Sweet; Patricia T Bozza; Steven P Gross; Robert G Parton; Albert Pol
Journal:  Science       Date:  2020-10-16       Impact factor: 47.728

2.  Elevation of JAML Promotes Diabetic Kidney Disease by Modulating Podocyte Lipid Metabolism.

Authors:  Yi Fu; Yu Sun; Mei Wang; Yunfeng Hou; Wei Huang; Di Zhou; Ziying Wang; Shuting Yang; Wei Tang; Junhui Zhen; Yujia Li; Xiaojie Wang; Min Liu; Yan Zhang; Baobao Wang; Guangyi Liu; Xiao Yu; Jinpeng Sun; Chun Zhang; Fan Yi
Journal:  Cell Metab       Date:  2020-11-12       Impact factor: 27.287

3.  Downregulation of PTEN promotes podocyte endocytosis of lipids aggravating obesity-related glomerulopathy.

Authors:  Yuanyuan Shi; Chen Wang; Xiaoshuang Zhou; Yafeng Li; Yuehong Ma; Rui Zhang; Rongshan Li
Journal:  Am J Physiol Renal Physiol       Date:  2019-12-09

4.  The TRPC6-AMPK Pathway is Involved in Insulin-Dependent Cytoskeleton Reorganization and Glucose Uptake in Cultured Rat Podocytes.

Authors:  Patrycja Rachubik; Maria Szrejder; Dorota Rogacka; Irena Audzeyenka; Michał Rychłowski; Stefan Angielski; Agnieszka Piwkowska
Journal:  Cell Physiol Biochem       Date:  2018-11-19

5.  Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol.

Authors:  Khalidur Rahman; Chirayu Desai; Smita S Iyer; Natalie E Thorn; Pradeep Kumar; Yunshan Liu; Tekla Smith; Andrew S Neish; Hongliang Li; Shiyun Tan; Pengbo Wu; Xiaoxiong Liu; Yuanjie Yu; Alton B Farris; Asma Nusrat; Charles A Parkos; Frank A Anania
Journal:  Gastroenterology       Date:  2016-06-21       Impact factor: 22.682

6.  Dapagliflozin in Patients with Chronic Kidney Disease.

Authors:  Hiddo J L Heerspink; Bergur V Stefánsson; Ricardo Correa-Rotter; Glenn M Chertow; Tom Greene; Fan-Fan Hou; Johannes F E Mann; John J V McMurray; Magnus Lindberg; Peter Rossing; C David Sjöström; Roberto D Toto; Anna-Maria Langkilde; David C Wheeler
Journal:  N Engl J Med       Date:  2020-09-24       Impact factor: 91.245

7.  ATP-binding cassette A1 deficiency causes cardiolipin-driven mitochondrial dysfunction in podocytes.

Authors:  G Michelle Ducasa; Alla Mitrofanova; Shamroop K Mallela; Xiaochen Liu; Judith Molina; Alexis Sloan; Christopher E Pedigo; Mengyuan Ge; Javier Varona Santos; Yanio Hernandez; Jin-Ju Kim; Cyrille Maugeais; Armando J Mendez; Viji Nair; Matthias Kretzler; George W Burke; Robert G Nelson; Yu Ishimoto; Reiko Inagi; Santanu Banerjee; Shaoyi Liu; Hazel H Szeto; Sandra Merscher; Flavia Fontanesi; Alessia Fornoni
Journal:  J Clin Invest       Date:  2019-07-22       Impact factor: 19.456

8.  Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models.

Authors:  Mario Schiffer; Beina Teng; Changkyu Gu; Valentina A Shchedrina; Marina Kasaikina; Vincent A Pham; Nils Hanke; Song Rong; Faikah Gueler; Patricia Schroder; Irini Tossidou; Joon-Keun Park; Lynne Staggs; Hermann Haller; Sergej Erschow; Denise Hilfiker-Kleiner; Changli Wei; Chuang Chen; Nicholas Tardi; Samy Hakroush; Martin K Selig; Aleksandr Vasilyev; Sandra Merscher; Jochen Reiser; Sanja Sever
Journal:  Nat Med       Date:  2015-05-11       Impact factor: 53.440

9.  Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism.

Authors:  Rebecca Bertolio; Francesco Napoletano; Miguel Mano; Sebastian Maurer-Stroh; Marco Fantuz; Alessandro Zannini; Silvio Bicciato; Giovanni Sorrentino; Giannino Del Sal
Journal:  Nat Commun       Date:  2019-03-22       Impact factor: 14.919

10.  The diabetes medication canagliflozin promotes mitochondrial remodelling of adipocyte via the AMPK-Sirt1-Pgc-1α signalling pathway.

Authors:  Xuping Yang; Qinhui Liu; Yanping Li; Qin Tang; Tong Wu; Lei Chen; Shiyun Pu; Yingnan Zhao; Guorong Zhang; Cuiyuan Huang; Jinhang Zhang; Zijing Zhang; Ya Huang; Min Zou; Xiongjie Shi; Wei Jiang; Rui Wang; Jinhan He
Journal:  Adipocyte       Date:  2020-12       Impact factor: 4.534

  10 in total
  3 in total

Review 1.  The Updates of Podocyte Lipid Metabolism in Proteinuric Kidney Disease.

Authors:  Yu Sun; Sijia Cui; Yunfeng Hou; Fan Yi
Journal:  Kidney Dis (Basel)       Date:  2021-09-01

2.  Twist1 downregulation of PGC-1α decreases fatty acid oxidation in tubular epithelial cells, leading to kidney fibrosis.

Authors:  Limin Liu; Xiaoxuan Ning; Lei Wei; Ying Zhou; Lijuan Zhao; Feng Ma; Ming Bai; Xiaoxia Yang; Di Wang; Shiren Sun
Journal:  Theranostics       Date:  2022-05-01       Impact factor: 11.600

3.  Anti-TWEAK Antibody Alleviates Renal Interstitial Fibrosis by Increasing PGC-1α Expression in Lupus Nephritis.

Authors:  Leixi Xue; Yi Zhang; Jiajun Xu; Wentian Lu; Qing Wang; Jinxiang Fu; Zhichun Liu
Journal:  J Inflamm Res       Date:  2021-03-26
  3 in total

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