Literature DB >> 33263140

Surgical treatment of colonic Crohn's disease: a national snapshot study.

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Abstract

AIM: The different surgical options for patients with colonic Crohn's disease (CD) include segmental colectomy, subtotal colectomy or proctocolectomy with end ileostomy. We present a national, multicentre study, promoted by the Italian Society of Colorectal Surgery with the aim to collect benchmark data and national variations on multidisciplinary management and postoperative outcomes of patients undergoing surgery for colonic CD.
METHODS: All adult patients having elective surgery for colonic CD from June 2018 to May 2019 were eligible for participation in this retrospective study. The primary outcome measure was postoperative morbidity within 30 days of surgery.
RESULTS: One hundred twenty-two patients were included: 55 subtotal colectomy, 30 segmental colectomy, 25 proctectomy and 12 proctocolectomy. Eighty-six patients (70.4%) were discussed at the inflammatory bowel disease (IBD) multidisciplinary team meeting (MDT) prior to surgery. This ranged from 76.6% for segmental colectomy to 60% for subtotal colectomy, 66.6% for proctocolectomy and 48% for proctectomy. The proportion of patients counselled by a stoma nurse preoperatively was 50%. Laparoscopy was associated with reduced postoperative morbidity (p = 0.017) and shorter length of hospital stay (p < 0.001), whilst pre-operative anti-TNF was associated with Dindo-Clavien ≥ 3 complications (p = 0.023) and longer in-hospital stay (p = 0.007). The main procedure performed (segmental colectomy, subtotal colectomy, proctocolectomy or proctectomy) was not associated with postoperative morbidity (p = 0.626).
CONCLUSIONS: Surgery for colonic CD has a high rate of postoperative complications. Almost a third of the patients were not preoperatively discussed at the IBD MDT, whilst the use of minimally invasive surgery for surgical treatment of colonic CD ranges from 40 to 66%.

Entities:  

Keywords:  Crohn’s colitis; Crohn’s disease; Inflammatory bowel disease; National audit; Proctocolectomy; Segmental colectomy

Year:  2020        PMID: 33263140     DOI: 10.1007/s00423-020-02038-z

Source DB:  PubMed          Journal:  Langenbecks Arch Surg        ISSN: 1435-2443            Impact factor:   3.445


  7 in total

1.  Clinical Practice Guideline for the Surgical Management of Crohn's Disease.

Authors:  Scott Strong; Scott R Steele; Marylise Boutrous; Liliana Bordineau; Jonathan Chun; David B Stewart; Jon Vogel; Janice F Rafferty
Journal:  Dis Colon Rectum       Date:  2015-11       Impact factor: 4.585

2.  Stepwise Training in Laparoscopic Surgery for Complex Ileocolonic Crohn's Disease: Analysis of 127 Training Episodes.

Authors:  Valerio Celentano; Karen G Flashman
Journal:  J Surg Educ       Date:  2019-03-28       Impact factor: 2.891

Review 3.  Inflammatory bowel disease (IBD) position statement of the Italian Society of Colorectal Surgery (SICCR): general principles of IBD management.

Authors:  G Pellino; D S Keller; G M Sampietro; V Annese; M Carvello; V Celentano; C Coco; F Colombo; N Cracco; F Di Candido; M Franceschi; S Laureti; G Mattioli; L Pio; G Sciaudone; G Sica; V Villanacci; R Zinicola; S Leone; S Danese; A Spinelli; G Delaini; F Selvaggi
Journal:  Tech Coloproctol       Date:  2020-01-25       Impact factor: 3.781

4.  Risk of postoperative morbidity in patients having bowel resection for colonic Crohn's disease.

Authors:  Igors Iesalnieks; A Spinelli; M Frasson; F Di Candido; B Scheef; N Horesh; M Iborra; H J Schlitt; A El-Hussuna
Journal:  Tech Coloproctol       Date:  2018-12-12       Impact factor: 3.781

Review 5.  Segmental Resection versus Total Proctocolectomy for Crohn's Colitis: What is the Best Operation in the Setting of Medically Refractory Disease or Dysplasia?

Authors:  Amy L Lightner
Journal:  Inflamm Bowel Dis       Date:  2018-02-15       Impact factor: 5.325

6.  ECCO Guidelines on Therapeutics in Crohn's Disease: Surgical Treatment.

Authors:  Michel Adamina; Stefanos Bonovas; Tim Raine; Antonino Spinelli; Janindra Warusavitarne; Alessandro Armuzzi; Oliver Bachmann; Palle Bager; Livia Biancone; Bernd Bokemeyer; Peter Bossuyt; Johan Burisch; Paul Collins; Glen Doherty; Alaa El-Hussuna; Pierre Ellul; Gionata Fiorino; Cornelia Frei-Lanter; Federica Furfaro; Christian Gingert; Paolo Gionchetti; Javier P Gisbert; Fernando Gomollon; Marien González Lorenzo; Hannah Gordon; Tibor Hlavaty; Pascal Juillerat; Konstantinos Katsanos; Uri Kopylov; Eduards Krustins; Torsten Kucharzik; Theodore Lytras; Christian Maaser; Fernando Magro; John Kenneth Marshall; Pär Myrelid; Gianluca Pellino; Isadora Rosa; Joao Sabino; Edoardo Savarino; Laurents Stassen; Joana Torres; Mathieu Uzzan; Stephan Vavricka; Bram Verstockt; Oded Zmora
Journal:  J Crohns Colitis       Date:  2020-02-10       Impact factor: 9.071

7.  Establishing Key Performance Indicators [KPIs] and Their Importance for the Surgical Management of Inflammatory Bowel Disease-Results From a Pan-European, Delphi Consensus Study.

Authors:  Pritesh S Morar; James Hollingshead; Willem Bemelman; Nick Sevdalis; Thomas Pinkney; Graeme Wilson; Malcolm Dunlop; R Justin Davies; Richard Guy; Nicola Fearnhead; Steven Brown; Janindra Warusavitarne; Cathryn Edwards; Omar Faiz
Journal:  J Crohns Colitis       Date:  2017-10-27       Impact factor: 9.071

  7 in total
  2 in total

Review 1.  Prehabilitation prior to intestinal resection in Crohn's disease patients: An opinion review.

Authors:  Michiel T J Bak; Marit F E Ruiterkamp; Oddeke van Ruler; Marjo J E Campmans-Kuijpers; Bart C Bongers; Nico L U van Meeteren; C Janneke van der Woude; Laurents P S Stassen; Annemarie C de Vries
Journal:  World J Gastroenterol       Date:  2022-06-14       Impact factor: 5.374

2.  Pretreatment with millet-derived selenylated soluble dietary fiber ameliorates dextran sulfate sodium-induced colitis in mice by regulating inflammation and maintaining gut microbiota balance.

Authors:  Weihao Wang; Fang Kou; Juan Wang; Zhigang Quan; Shuting Zhao; Yifei Wang; Xin Hu; Hunan Sun; Longkui Cao
Journal:  Front Nutr       Date:  2022-09-07
  2 in total

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