Ned Chandler-Mather1, Stefano Occhipinti2, Caroline Donovan3, Doug Shelton4, Sharon Dawe5. 1. School of Applied Psychology, Griffith University, Brisbane, Australia. Electronic address: ned.chandler-mather@griffithuni.edu.au. 2. School of Applied Psychology, Griffith University, Brisbane, Australia; EPIC Health Systems, Menzies Health Institute Queensland, Australia. 3. School of Applied Psychology, Griffith University, Brisbane, Australia. 4. Gold Coast University Hospital, Southport, Australia. 5. School of Applied Psychology, Griffith University, Brisbane, Australia; The Hopkins Centre, Griffith University.
Abstract
OBJECTIVE: To investigate the association between dose and frequency of prenatal alcohol exposure (PAE) and sleep problems in children, after controlling for established risk factors for sleep problems. METHODS: Data from the birth cohort of the Longitudinal Study of Australian Children (LSAC) was used. Mothers of 3447 children provided information on alcohol consumption during pregnancy, children's sleep problems from 2- to 9-years, and potential confounders associated with sleep problems. Children were classified into PAE groups based on distinct patterns of maternal drinking during pregnancy: abstinent, occasional, low, moderate, and heavy. The effect of PAE on the number and persistence of sleep problems across childhood (2-9 years) was examined. RESULTS: After controlling for multiple covariates that impact sleep, children with heavy PAE had 1.13 more sleep problems across childhood (2-9 years) relative to children whose mothers were abstainers, in particular 0.37 more at 2- to 3-years (0.504, 95 % CI 0.053, 0.956), and 0.34 more at 6- to 7-years (0.847, 95 % CI 0.299, 1.396). Compared to children of abstainers, heavy PAE increases the probability of having persistent sleep problems from 2- to 9-years by 22.57 %. No negative associations between moderate or low PAE and sleep were observed. Parenting, family, economic, and child health factors also significantly affected child sleep. CONCLUSION: Heavy PAE was associated with significantly more sleep problems across childhood and a higher probability of reporting persistent sleep problems, relative to children with no PAE. Implications for the understanding and management of sleep in young children with PAE and FASD are discussed.
OBJECTIVE: To investigate the association between dose and frequency of prenatal alcohol exposure (PAE) and sleep problems in children, after controlling for established risk factors for sleep problems. METHODS: Data from the birth cohort of the Longitudinal Study of Australian Children (LSAC) was used. Mothers of 3447 children provided information on alcohol consumption during pregnancy, children's sleep problems from 2- to 9-years, and potential confounders associated with sleep problems. Children were classified into PAE groups based on distinct patterns of maternal drinking during pregnancy: abstinent, occasional, low, moderate, and heavy. The effect of PAE on the number and persistence of sleep problems across childhood (2-9 years) was examined. RESULTS: After controlling for multiple covariates that impact sleep, children with heavy PAE had 1.13 more sleep problems across childhood (2-9 years) relative to children whose mothers were abstainers, in particular 0.37 more at 2- to 3-years (0.504, 95 % CI 0.053, 0.956), and 0.34 more at 6- to 7-years (0.847, 95 % CI 0.299, 1.396). Compared to children of abstainers, heavy PAE increases the probability of having persistent sleep problems from 2- to 9-years by 22.57 %. No negative associations between moderate or low PAE and sleep were observed. Parenting, family, economic, and child health factors also significantly affected child sleep. CONCLUSION: Heavy PAE was associated with significantly more sleep problems across childhood and a higher probability of reporting persistent sleep problems, relative to children with no PAE. Implications for the understanding and management of sleep in young children with PAE and FASD are discussed.
Authors: Katarzyna Anna Dylag; Bożena Bando; Zbigniew Baran; Paulina Dumnicka; Katarzyna Kowalska; Paulina Kulaga; Katarzyna Przybyszewska; Jakub Radlinski; Sylvia Roozen; Leopold Curfs Journal: Ital J Pediatr Date: 2021-05-17 Impact factor: 2.638
Authors: Madeleine F Cohen; Anne L Dunlop; Dayna A Johnson; Alexis Dunn Amore; Elizabeth J Corwin; Patricia A Brennan Journal: Int J Environ Res Public Health Date: 2022-03-28 Impact factor: 3.390