Literature DB >> 33256428

Comparative effects on pain arising from injury to the knee meniscus in adults: A systematic review and network meta-analysis.

Yongni Zhang1, Wuting Cao2, Qin Cao3, Yi Zhu4.   

Abstract

OBJECTIVE: To identify the most effective pain management method for meniscus injuries by comparing pain relief observed with several common interventions including combined different combinations of surgery and exercise, surgery alone, supervised exercise alone and home exercise alone.
METHODS: PubMed, Embase, CINAHL, Cochrane Library, Web of Science, SportDiscus, and PEDro were searched from database inception through October 15, 2020. Randomized controlled trials investigating the effect of surgery and exercise for meniscus injuries by using the visual analogue scale (VAS) assessment were eligible for inclusion. Primary outcome was mean change in VAS score from baseline. Comparisons between interventions were made through use of random-effects network meta-analysis over the short-term (three months) and mid-term (12 months). Relative ranking of therapies was assessed by the surface-under-the-cumulative ranking possibilities. All reference lists of included studies were hand-searched.
RESULTS: We investigated six RCTs (total n = 796 patients). No significant difference was found between different treatments of pain control in three months and 12 months. The surface under the cumulative ranking curves suggested that supervised exercise combined with surgery was considered most likely to overshadow other treatments in reducing short-term pain (surface under cumulative ranking curve (SUCRA) values: 98.1; mean ranks: 1.1) and mid-term pain (SUCRA values: 97.2; mean rank: 1.1).
CONCLUSION: There is not sufficient evidence to identify any preferred or more effective surgical and/or exercise-based treatment program.

Entities:  

Keywords:  meniscus; meta-analysis; pain

Mesh:

Year:  2020        PMID: 33256428     DOI: 10.1177/0269215520976649

Source DB:  PubMed          Journal:  Clin Rehabil        ISSN: 0269-2155            Impact factor:   3.477


  1 in total

1.  Knockdown of hsa_circ_0037658 inhibits the progression of osteoarthritis via inducing autophagy.

Authors:  Cong Sui; Debao Liu; Yukang Que; Shenglin Xu; Yong Hu
Journal:  Hum Cell       Date:  2020-09-27       Impact factor: 4.174

  1 in total

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