| Literature DB >> 33255383 |
Megan Cross1, Shu-Kay Ng1, Paul Scuffham1.
Abstract
International governments' COVID-19 responses must balance human and economic health. Beyond slowing viral transmission, strict lockdowns have severe economic consequences. This work investigated response stringency, quantified by the Oxford COVID-19 Government Response Tracker's Stringency Index, and examined how restrictive interventions affected infection rates and gross domestic product (GDP) in China and OECD countries. Accounting for response timing, China imposed the most stringent restrictions, while Sweden and Japan were the least stringent. Expected GDP declines range from -8% (Japan) to -15.4% (UK). While greater restrictions generally slowed viral transmission, they failed to reach statistical significance and reduced GDP (p = 0.006). Timing was fundamental: governments who responded to the pandemic faster saw greater reductions in viral transmission (p = 0.013), but worse decreases in GDP (p = 0.044). Thus, response stringency has a greater effect on GDP than infection rates, which are instead affected by the timing of COVID-19 interventions. Attempts to mitigate economic impacts by delaying restrictions or decreasing stringency may buoy GDP in the short term but increase infection rates, the longer-term economic consequences of which are not yet fully understood. As highly restrictive interventions were successful in some but not all countries, decision-makers must consider whether their strategies are appropriate for the country on health and economic grounds.Entities:
Keywords: COVID-19; GDP; infection rate; stringency index
Mesh:
Year: 2020 PMID: 33255383 PMCID: PMC7727819 DOI: 10.3390/ijerph17238725
Source DB: PubMed Journal: Int J Environ Res Public Health ISSN: 1660-4601 Impact factor: 3.390
Characteristics of Oxford Stringency Index for China and 37 OECD countries from January to July 2020.
| Country | Max. Score | # Days to Respond | # Days to Max. a | # Days of Response | # Days at Max. | Response Escalation b (Days) | Escalation Speed c (SI/Day) | AUC d | AUCav e | |
|---|---|---|---|---|---|---|---|---|---|---|
| To Pandemic a | To First Local Case | |||||||||
| Asia | ||||||||||
| China | 82 | 5 | 49 | 86 | 188 | 47 | 81 | 1 | 12,391 | 66 |
| Israel | 94 | 27 | −26 | 99 | 166 | 6 | 72 | 1.3 | 10,078 | 61 |
| Japan | 47 | 7 | −8 | 107 | 186 | 28 | 100 | 0.5 | 5705 | 31 |
| Korea | 82 | 31 | 11 | 97 | 162 | 12 | 66 | 1.2 | 8397 | 52 |
| Turkey | 78 | 24 | −48 | 102 | 169 | 4 | 78 | 1 | 8797 | 52 |
| Europe | ||||||||||
| Austria | 85 | 55 | −2 | 76 | 138 | 29 | 21 | 4.1 | 7658 | 55 |
| Belgium | 81 | 28 | −7 | 80 | 165 | 46 | 52 | 1.6 | 8661 | 52 |
| Czech Republic | 82 | 24 | −38 | 83 | 169 | 10 | 59 | 1.4 | 7509 | 44 |
| Denmark | 72 | 58 | 0 | 78 | 135 | 28 | 20 | 3.6 | 8077 | 60 |
| Estonia | 78 | 72 | 13 | 89 | 121 | 29 | 17 | 4.6 | 6447 | 53 |
| Finland | 60 | 27 | −3 | 88 | 166 | 18 | 61 | 1 | 6323 | 38 |
| France | 91 | 23 | −2 | 77 | 170 | 55 | 54 | 1.7 | 9832 | 58 |
| Germany | 73 | 24 | −4 | 82 | 169 | 43 | 58 | 1.3 | 7729 | 46 |
| Greece | 84 | 56 | −2 | 83 | 137 | 42 | 27 | 3.1 | 8196 | 60 |
| Hungary | 77 | 59 | −32 | 88 | 134 | 37 | 29 | 2.6 | 7908 | 59 |
| Iceland | 54 | 23 | −26 | 80 | 170 | 45 | 57 | 0.9 | 6105 | 36 |
| Ireland | 91 | 35 | −26 | 97 | 158 | 42 | 62 | 1.5 | 9074 | 57 |
| Italy | 94 | 23 | −8 | 103 | 170 | 22 | 80 | 1.2 | 10,333 | 61 |
| Latvia | 66 | 31 | −8 | 87 | 162 | 46 | 56 | 1.2 | 6930 | 43 |
| Lithuania | 87 | 57 | −2 | 101 | 136 | 4 | 44 | 2 | 8084 | 59 |
| Luxembourg | 80 | 65 | 4 | 77 | 128 | 34 | 12 | 6.6 | 6904 | 54 |
| Netherlands | 80 | 66 | 7 | 91 | 127 | 41 | 25 | 3.2 | 8065 | 64 |
| Norway | 80 | 31 | −27 | 84 | 162 | 27 | 53 | 1.5 | 7150 | 44 |
| Poland | 83 | 23 | −41 | 100 | 170 | 46 | 77 | 1.1 | 8409 | 49 |
| Portugal | 88 | 26 | −37 | 100 | 167 | 8 | 74 | 1.2 | 9191 | 55 |
| Slovak Republic | 87 | 27 | −40 | 99 | 166 | 6 | 72 | 1.2 | 7850 | 47 |
| Slovenia | 90 | 64 | −1 | 90 | 129 | 21 | 26 | 3.5 | 7031 | 55 |
| Spain | 85 | 31 | −1 | 90 | 162 | 35 | 59 | 1.4 | 8730 | 54 |
| Sweden | 46 | 69 | 37 | 95 | 124 | 70 | 26 | 1.8 | 4861 | 39 |
| Switzerland | 73 | 56 | −1 | 77 | 137 | 41 | 21 | 3.5 | 7466 | 54 |
| UK | 76 | 33 | 2 | 86 | 160 | 48 | 53 | 1.4 | 8364 | 52 |
| North America | ||||||||||
| Canada | 75 | 22 | −4 | 92 | 171 | 3 | 70 | 1.1 | 8243 | 48 |
| Mexico | 82 | 59 | −1 | 90 | 134 | 63 | 31 | 2.7 | 8221 | 61 |
| USA | 73 | 33 | 12 | 81 | 160 | 86 | 48 | 1.5 | 8544 | 53 |
| South America | ||||||||||
| Chile | 89 | 74 | 10 | 185 | 119 | 4 | 111 | 0.8 | 8443 | 71 |
| Colombia | 91 | 21 | −46 | 118 | 172 | 9 | 97 | 0.9 | 10,168 | 59 |
| Oceania | ||||||||||
| Australia | 76 | 25 | 0 | 93 | 168 | 16 | 68 | 1.1 | 8153 | 49 |
| New Zealand | 96 | 22 | −37 | 86 | 171 | 33 | 64 | 1.5 | 7466 | 44 |
| Statistics | ||||||||||
| Median | 81.5 | 31 | −2.5 | 89.5 | 162 | 31 | 57.5 | 1.4 | 8118.5 | 53.5 |
| Range | 46–96 | 5–74 | −48–49 | 76–185 | 119–188 | 3–86 | 12–111 | 0.5–6.6 | 4861–12,391 | 31–71 |
| IQR f | 13 | 34 | 33 | 16 | 34 | 34 | 44 | 1.5 | 1291 | 12 |
| ICC g | <0.001 | 0.195 | <0.001 | 0.742 * | 0.195 | 0.22 | 0.551 * | 0.108 | 0.076 | 0.081 |
a Number of days since 1 January 2020; b Response escalation is the time taken to reach max SI after a response was initiated; c Escalation speed = max score/response escalation; considers the rate at which each country increased its stringency; d Area under curve (AUC) quantifies the stringency level and duration of each pandemic response; e AUCav = AUC/duration of response; is a measure of average stringency in a response period; f Interquartile range (IQR); g Intra-cluster correlation coefficient (ICC) measures the extent of correlation within continents (* p < 0.05). Data were downloaded from [10].
Characteristics of Oxford Stringency Index for the focus countries from January to July 2020.
| Country | Max. Score | # Days to Respond to First Local Case | # Days to Max. a | # Days at Max. | Response Escalation b (Days) | AUC c | AUCav d |
|---|---|---|---|---|---|---|---|
| Asia | |||||||
| China | 82 | 49 | 86 | 47 | 81 | 12,391 | 66 |
| Japan | 47 | −8 | 107 | 28 | 100 | 5705 | 31 |
| Europe | |||||||
| Finland | 60 | −3 | 88 | 18 | 61 | 6323 | 38 |
| Norway | 80 | −27 | 84 | 27 | 53 | 7150 | 44 |
| Sweden | 46 | 37 | 95 | 70 | 26 | 4861 | 39 |
| UK | 76 | 2 | 86 | 48 | 53 | 8364 | 52 |
| America | |||||||
| USA | 73 | 12 | 81 | 86 | 48 | 8544 | 53 |
| Colombia | 91 | −46 | 118 | 9 | 97 | 10,168 | 59 |
| Australasia | |||||||
| Australia | 76 | 0 | 93 | 16 | 68 | 8153 | 49 |
| Statistics e | |||||||
| Median | 76 | 0 | 88 | 28 | 61 | 8153 | 49 |
| Range | 46–91 | −46–49 | 81–118 | 9–86 | 26–100 | 4861–12,391 | 31–66 |
| IQR f | 20 | 20 | 9 | 30 | 28 | 2221 | 14 |
| ICC g | <0.001 | <0.001 | 0.561 | 0.391 | 0.668 * | <0.001 | <0.001 |
a Number of days since 1 January 2020; b Response escalation is the time taken to reach max SI after a response was initiated; c Area under curve (AUC) quantifies the stringency level and duration of each pandemic response; d AUCav = AUC/duration of response; is a measure of average stringency in a response period; e Statistics were calculated for data from the focus countries (see Table A1 for China and 37 OECD countries); f Interquartile range (IQR); g Intra-cluster correlation coefficient (ICC) measures the extent of correlation within continents (* p < 0.05). Data were downloaded from [10].
Figure 1Stringency index and infection rates. The rate of new cases is shown in black for periods of one month before and one month after a period at maximum stringency index (SI) [10,12], which is highlighted in red. SI over the same period is overlaid in blue and scaled from 0 to 100 in all plots to enable comparisons.
Average number of daily cases per million people before, during and after periods at maximum stringency.
| Average Daily Cases Per Million People | |||
|---|---|---|---|
| Before Max SI a | At Max SI b | After Max SI a | |
| USA | 2.6 | 72.9 | 129.8 |
| Colombia | 3.0 | 6.2 | 16.9 |
| UK | 8.4 | 61.2 | 27.5 |
| Sweden | 17.4 | 59.2 | 89.7 |
| Finland | 8.4 | 22.4 | 18.2 |
| Norway | 15.3 | 32.6 | 8.7 |
| China c | 1.7 | 0.1 | 0.0 |
| Japan | 1.9 | 2.3 | 0.4 |
| Australia c | 5.9 | 6.0 | 0.9 |
Case data were downloaded from the Oxford Martin School [12]; a Daily case rates averaged over a 30-day period; b Daily case rates averaged over the duration of each country’s period at maximum SI; c Case rates are presented for the first period at maximum SI.
Results of negative binomial regression models on total infections in 38 countries from 1 June to 23 July 2020.
| Risk Factor a | Rate Ratio (95% CI) | |
|---|---|---|
| GDP (per USD 1000) ^ | 1.024 (1.000, 1.052) | 0.078 |
| Democracy index ^ | 1.042 (1.004, 1.082) * | 0.030 |
| Average temperature (Jan–Mar) | 1.079 (0.986, 1.181) | 0.099 |
| Average temperature (Jan–Jun) | 1.076 (0.955, 1.213) | 0.228 |
| Population density ^ | 1.000 (0.996, 1.004) | 0.861 |
| Median age | 0.850 (0.766, 0.943) * | 0.002 |
| Aged > 65 | 0.941 (0.807, 1.098) | 0.442 |
| Aged > 70 | 0.944 (0.764, 1.167) | 0.596 |
| Variable related to Oxford Stringency Index §: | ||
| Maximum scoreb | 0.988 (0.962, 1.015) | 0.376 |
| Time to respond (to pandemic) ^ | 1.028 (1.006, 1.050) * | 0.013 |
| Time to respond (to first local case) b | 1.011 (0.995, 1.027) | 0.194 |
| Time to Maximum score c | 1.072 (1.023, 1.124) * | 0.004 |
| Response escalation b | 0.993 (0.972, 1.015) | 0.547 |
| Period at Maximum score b | 1.004 (0.982, 1.026) | 0.725 |
| AUC ^ | 0.9997 (0.9993, 1.0000) | 0.084 |
| AUCav b | 0.983 (0.939, 1.028) | 0.448 |
Data were downloaded from the Oxford COVID-19 Government Response Tracker [10]. ^ Negative binomial mixed-effect model (with significant continental effect); * p < 0.05; § SI measures up to 31 May 2020; a Univariate analysis unless otherwise stated; b Multivariate analysis: adjusted for median age; c Multivariate analysis: adjusted for GDP and median age.
Figure 2The effect of COVID-19 responses on annual GDP growth rates. Annual GDP growth rates were estimated by the OECD.13 (a) Results of multilevel mixed-effect linear regression models of change in annual growth rate 2019–2020 per interquartile range (IQR) due to a double-hit scenario (38 countries; multivariate analyses adjusted for GDP). Error bars show 95% confidence intervals; * p < 0.05. The difference between the 2019 and 2020 growth rates is shown against (b) response stringency and duration (area under the curve; AUC) and (c) the time for each country to respond to the pandemic (stringency index > 0); this includes both preventative restrictions that may have preceded confirmed cases in those countries.
Results of linear regression models on change in annual growth rate 2019–2020 due to a double-hit scenario (38 countries).
| Risk Factor | Increase in GDP in % (95% CI) | |
|---|---|---|
| GDP (per $1000) ^ | 0.052 (0.000, 0.100) * | 0.034 |
| Democracy index ^ | 0.044 (−0.011, 0.100) | 0.119 |
| Average temperature (Jan–Mar) ^ | −0.031 (−0.153, 0.091) | 0.616 |
| Average temperature (Jan–Jun) ^ | −0.066 (−0.251, 0.119) | 0.486 |
| Population density ^ | 0.002 (−0.004, 0.008) | 0.461 |
| Median age ^ | −0.002 (−0.196, 0.193) | 0.986 |
| Aged > 65 ^ | −0.033 (−0.237, 0.170) | 0.748 |
| Aged > 70 ^ | −0.027 (−0.294, 0.239) | 0.841 |
| Variable related to Oxford Stringency Index §: | ||
| Maximum score ^ | −0.076 (−0.135, −0.016) * | 0.012 |
| Time to respond (to pandemic) ^,a | 0.039 (0.001, 0.076) * | 0.044 |
| Time to respond (to first local case) ^ | 0.037 (0.004, 0.068) * | 0.026 |
| Time to maximum score ^,a | 0.020 (−0.030, 0.069) | 0.442 |
| Response escalation ^ | −0.032 (−0.067, 0.004) | 0.080 |
| Period at maximum score ^,a | −0.0007 (−0.039, 0.037) | 0.970 |
| AUC ^ | −0.0007 (−0.0012, −0.0002) * | 0.006 |
| AUCav ^,a | −0.028 (−0.113, 0.058) | 0.526 |
Note: ^ linear mixed-effect model (with significant continental effect); * p < 0.05; § SI measures up to 6 July 2020; Univariate analysis unless otherwise stated; a Multivariate analysis: Adjusted for GDP; Data were downloaded from [10,13].