Literature DB >> 33255243

Detection of Ebola Virus Antibodies in Fecal Samples of Great Apes in Gabon.

Illich M Mombo1, Matthieu Fritz2, Pierre Becquart2, Florian Liegeois2, Eric Elguero2, Larson Boundenga1, Telstar N Mebaley1, Franck Prugnolle2, Gael D Maganga1,3, Eric M Leroy2.   

Abstract

Based on a large study conducted on wild great ape fecal samples collected in regions of Gabon where previous human outbreaks of Ebola virus disease have occurred between 1994 and 2002, we provide evidence for prevalence of Zaire ebolavirus (EBOV)-specific antibodies of 3.9% (immunoglobulin G (IgG)) and 3.5% (immunoglobulin M (IgM)) in chimpanzees and 8.8% (IgG) and 2.4% (IgM) in gorillas. Importantly, we observed a high local prevalence (31.2%) of anti-EBOV IgG antibodies in gorilla samples. This high local rate of positivity among wild great apes raises the question of a spatially and temporally localized increase in EBOV exposure risk and the role that can be played by these animals as sentinels of the virus's spread or reemergence in a given area.

Entities:  

Keywords:  Africa; Ebola; Luminex; great ape

Mesh：

Substances：

Year:  2020        PMID： 33255243      PMCID： PMC7761173          DOI： 10.3390/v12121347

Source DB:  PubMed          Journal:  Viruses        ISSN： 1999-4915            Impact factor:   5.048


  33 in total

1.  Morbidity and mortality of wild animals in relation to outbreaks of Ebola haemorrhagic fever in Gabon, 1994-2003.

Authors:  Sally A Lahm; Maryvonne Kombila; Robert Swanepoel; Richard F W Barnes
Journal:  Trans R Soc Trop Med Hyg       Date:  2006-09-28       Impact factor: 2.184

2.  Catastrophic ape decline in western equatorial Africa.

Authors:  Peter D Walsh; Kate A Abernethy; Magdalena Bermejo; Rene Beyers; Pauwel De Wachter; Marc Ella Akou; Bas Huijbregts; Daniel Idiata Mambounga; Andre Kamdem Toham; Annelisa M Kilbourn; Sally A Lahm; Stefanie Latour; Fiona Maisels; Christian Mbina; Yves Mihindou; Sosthène Ndong Obiang; Ernestine Ntsame Effa; Malcolm P Starkey; Paul Telfer; Marc Thibault; Caroline E G Tutin; Lee J T White; David S Wilkie
Journal:  Nature       Date:  2003-04-06       Impact factor: 49.962

3.  A serological survey of Ebola virus infection in central African nonhuman primates.

Authors:  E M Leroy; P Telfer; B Kumulungui; P Yaba; P Rouquet; P Roques; J-P Gonzalez; T G Ksiazek; P E Rollin; E Nerrienet
Journal:  J Infect Dis       Date:  2004-11-03       Impact factor: 5.226

4.  Is the Bombali virus pathogenic in humans?

Authors:  Henry J Martell; Stuart G Masterson; Jake E McGreig; Martin Michaelis; Mark N Wass
Journal:  Bioinformatics       Date:  2019-10-01       Impact factor: 6.937

5.  Multiple Ebola virus transmission events and rapid decline of central African wildlife.

Authors:  Eric M Leroy; Pierre Rouquet; Pierre Formenty; Sandrine Souquière; Annelisa Kilbourne; Jean-Marc Froment; Magdalena Bermejo; Sheilag Smit; William Karesh; Robert Swanepoel; Sherif R Zaki; Pierre E Rollin
Journal:  Science       Date:  2004-01-16       Impact factor: 47.728

6.  Spatial and temporal patterns of Zaire ebolavirus antibody prevalence in the possible reservoir bat species.

Authors:  X Pourrut; A Délicat; P E Rollin; T G Ksiazek; J-P Gonzalez; E M Leroy
Journal:  J Infect Dis       Date:  2007-11-15       Impact factor: 5.226

7.  Isolation and partial characterisation of a new strain of Ebola virus.

Authors:  B Le Guenno; P Formenty; P Formentry; M Wyers; P Gounon; F Walker; C Boesch
Journal:  Lancet       Date:  1995-05-20       Impact factor: 79.321

8.  A new approach for monitoring ebolavirus in wild great apes.

Authors:  Patricia E Reed; Sabue Mulangu; Kenneth N Cameron; Alain U Ondzie; Damien Joly; Magdalena Bermejo; Pierre Rouquet; Giulia Fabozzi; Michael Bailey; Zhimin Shen; Brandon F Keele; Beatrice Hahn; William B Karesh; Nancy J Sullivan
Journal:  PLoS Negl Trop Dis       Date:  2014-09-18

9.  Serological Detection of Ebola Virus Exposures in Native Non-human Primates of Southern Nigeria.

Authors:  B N Ogunro; B O Olugasa; E J Verschoor; A O Olarinmoye; I Theyse; H Niphuis
Journal:  J Epidemiol Glob Health       Date:  2018-12

10.  Mapping the zoonotic niche of Ebola virus disease in Africa.

Authors:  David M Pigott; Nick Golding; Adrian Mylne; Zhi Huang; Andrew J Henry; Daniel J Weiss; Oliver J Brady; Moritz U G Kraemer; David L Smith; Catherine L Moyes; Samir Bhatt; Peter W Gething; Peter W Horby; Isaac I Bogoch; John S Brownstein; Sumiko R Mekaru; Andrew J Tatem; Kamran Khan; Simon I Hay
Journal:  Elife       Date:  2014-09-08       Impact factor: 8.140
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  2 in total

1.  Estimation of Ebola's spillover infection exposure in Sierra Leone based on sociodemographic and economic factors.

Authors:  Sena Mursel; Nathaniel Alter; Lindsay Slavit; Anna Smith; Paolo Bocchini; Javier Buceta
Journal:  PLoS One       Date:  2022-09-01       Impact factor: 3.752

2.  Transmission models indicate Ebola virus persistence in non-human primate populations is unlikely.

Authors:  David T S Hayman; Reju Sam John; Pejman Rohani
Journal:  J R Soc Interface       Date:  2022-02-02       Impact factor: 4.293
  2 in total

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