Ruiyuan Zhang1, Huiying Liang1,2, Jinling Tang1,3. 1. Department of Clinical Data Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. 2. Guangdong Provincial Children's Medical Research Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. 3. School of Public Health and Primary Care, the Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.