Literature DB >> 3325050

Kinetic isotope effects and 'metabolic switching' in cytochrome P450-catalyzed reactions.

G T Miwa, A Y Lu.   

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Year:  1987        PMID: 3325050     DOI: 10.1002/bies.950070506

Source DB:  PubMed          Journal:  Bioessays        ISSN: 0265-9247            Impact factor:   4.345


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  14 in total

1.  Kinetic Deuterium Isotope Effects in Cytochrome P450 Reactions.

Authors:  Frederick P Guengerich
Journal:  Methods Enzymol       Date:  2017-07-18       Impact factor: 1.600

2.  Simultaneous measurement of CYP1A2 activity, regioselectivity, and coupling: Implications for environmental sensitivity of enzyme-substrate binding.

Authors:  Matthew J Traylor; Jack Chai; Douglas S Clark
Journal:  Arch Biochem Biophys       Date:  2010-10-08       Impact factor: 4.013

Review 3.  Kinetic deuterium isotope effects in cytochrome P450 oxidation reactions.

Authors:  F Peter Guengerich
Journal:  J Labelled Comp Radiopharm       Date:  2013-03-10       Impact factor: 1.921

Review 4.  The diverse chemistry of cytochrome P450 17A1 (P450c17, CYP17A1).

Authors:  Francis K Yoshimoto; Richard J Auchus
Journal:  J Steroid Biochem Mol Biol       Date:  2014-12-04       Impact factor: 4.292

5.  Parallel and competitive pathways for substrate desaturation, hydroxylation, and radical rearrangement by the non-heme diiron hydroxylase AlkB.

Authors:  Harriet L R Cooper; Girish Mishra; Xiongyi Huang; Marilla Pender-Cudlip; Rachel N Austin; John Shanklin; John T Groves
Journal:  J Am Chem Soc       Date:  2012-12-10       Impact factor: 15.419

6.  Oxidation of N-Nitrosoalkylamines by human cytochrome P450 2A6: sequential oxidation to aldehydes and carboxylic acids and analysis of reaction steps.

Authors:  Goutam Chowdhury; M Wade Calcutt; F Peter Guengerich
Journal:  J Biol Chem       Date:  2010-01-08       Impact factor: 5.157

7.  Oxidation of methyl and ethyl nitrosamines by cytochrome P450 2E1 and 2B1.

Authors:  Goutam Chowdhury; M Wade Calcutt; Leslie D Nagy; F Peter Guengerich
Journal:  Biochemistry       Date:  2012-12-04       Impact factor: 3.162

8.  Methylene Oxidation of Alkyl Sulfates by Cytochrome P450BM-3 and a Role for Conformational Selection in Substrate Recognition.

Authors:  F Peter Guengerich; Mostafa I Fekry
Journal:  ACS Catal       Date:  2020-04-02       Impact factor: 13.084

9.  Deuterium isotope effects in drug pharmacokinetics II: Substrate-dependence of the reaction mechanism influences outcome for cytochrome P450 cleared drugs.

Authors:  Hao Sun; David W Piotrowski; Suvi T M Orr; Joseph S Warmus; Angela C Wolford; Steven B Coffey; Kentaro Futatsugi; Yinsheng Zhang; Alfin D N Vaz
Journal:  PLoS One       Date:  2018-11-14       Impact factor: 3.240

10.  Kinetic analysis of lauric acid hydroxylation by human cytochrome P450 4A11.

Authors:  Donghak Kim; Gun-Su Cha; Leslie D Nagy; Chul-Ho Yun; F Peter Guengerich
Journal:  Biochemistry       Date:  2014-09-19       Impact factor: 3.162

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