Literature DB >> 33249904

IMPACT-Restart: the influence of COVID-19 on postoperative mortality and risk factors associated with SARS-CoV-2 infection after orthopaedic and trauma surgery.

Nicholas D Clement1, Andrew James Hall1, Navnit S Makaram1, Patrick G Robinson1, Robyn F L Patton2, Matthew Moran1, Gavin J Macpherson1, Andrew D Duckworth1,3, Paul J Jenkins4.   

Abstract

AIMS: The primary aim of this study was to assess the independent association of the coronavirus disease 2019 (COVID-19) on postoperative mortality for patients undergoing orthopaedic and trauma surgery. The secondary aim was to identify factors that were associated with developing COVID-19 during the postoperative period.
METHODS: A multicentre retrospective study was conducted of all patients presenting to nine centres over a 50-day period during the COVID-19 pandemic (1 March 2020 to 19 April 2020) with a minimum of 50 days follow-up. Patient demographics, American Society of Anesthesiologists (ASA) grade, priority (urgent or elective), procedure type, COVID-19 status, and postoperative mortality were recorded.
RESULTS: During the study period, 1,659 procedures were performed in 1,569 patients. There were 68 (4.3%) patients who were diagnosed with COVID-19. There were 85 (5.4%) deaths postoperatively. Patients who had COVID-19 had a significantly lower survival rate when compared with those without a proven SARS-CoV-2 infection (67.6% vs 95.8%, p < 0.001). When adjusting for confounding variables (older age (p < 0.001), female sex (p = 0.004), hip fracture (p = 0.003), and increasing ASA grade (p < 0.001)) a diagnosis of COVID-19 was associated with an increased mortality risk (hazard ratio 1.89, 95% confidence interval (CI) 1.14 to 3.12; p = 0.014). A total of 62 patients developed COVID-19 postoperatively, of which two were in the elective and 60 were in the urgent group. Patients aged > 77 years (odds ratio (OR) 3.16; p = 0.001), with increasing ASA grade (OR 2.74; p < 0.001), sustaining a hip (OR 4.56; p = 0.008) or periprosthetic fracture (OR 14.70; p < 0.001) were more likely to develop COVID-19 postoperatively.
CONCLUSION: Perioperative COVID-19 nearly doubled the background postoperative mortality risk following surgery. Patients at risk of developing COVID-19 postoperatively (patients > 77 years, increasing morbidity, sustaining a hip or periprosthetic fracture) may benefit from perioperative shielding. Cite this article: Bone Joint J 2020;102-B(12):1774-1781.

Entities:  

Keywords:  COVID-19; Elective; Mortality; Postoperative; Trauma

Mesh:

Year:  2020        PMID: 33249904     DOI: 10.1302/0301-620X.102B12.BJJ-2020-1395.R2

Source DB:  PubMed          Journal:  Bone Joint J        ISSN: 2049-4394            Impact factor:   5.082


  29 in total

1.  The IMPACT of COVID-19 on trauma & orthopaedic surgery provides lessons for future communicable disease outbreaks : minimum reporting standards, risk scores, fragility trauma services, and global collaboration.

Authors:  Andrew J Hall; Nick D Clement; Alasdair M J MacLullich; A Hamish R W Simpson; Tim O White; Andrew D Duckworth
Journal:  Bone Joint Res       Date:  2022-06       Impact factor: 4.410

2.  The Impact of COVID-19 on SARSCoV-2-Negative Elderly Patients with Hip Fractures: A Single-Center Retrospective Study from Shanghai, China.

Authors:  Jinhui Zhao; Qianying Cai; Dajun Jiang; Lingtian Wang; Haiyan He; Shengbao Chen; Weitao Jia; Changqing Zhang
Journal:  Clin Interv Aging       Date:  2022-07-01       Impact factor: 3.829

3.  The delivery of an emergency audit response to a communicable disease outbreak can inform future orthopaedic investigations and clinical practice : lessons from IMPACT Hip Fracture Global Audits.

Authors:  Andrew J Hall; Nick D Clement; Alasdair M J MacLullich; A H R W Simpson; Antony Johansen; Tim O White; Andrew D Duckworth
Journal:  Bone Joint Res       Date:  2022-06       Impact factor: 4.410

4.  Mortality escalates in patients of proximal femoral fractures with COVID-19: A systematic review and meta-analysis of 35 studies on 4255 patients.

Authors:  Mohit Kumar Patralekh; Vijay Kumar Jain; Karthikeyan P Iyengar; Gaurav Kumar Upadhyaya; Raju Vaishya
Journal:  J Clin Orthop Trauma       Date:  2021-04-20

5.  Did COVID-19 related delays in surgical management lead to patient morbidity in the orthopaedic oncological population?

Authors:  Michael J Fitzgerald; Howard J Goodman; Samuel Kenan; Shachar Kenan
Journal:  Bone Jt Open       Date:  2021-04

6.  Insights into patient preferences for elective surgery during the COVID-19 pandemic.

Authors:  Andrew James Hotchen; Saad A Khan; Maaz A Khan; Matthew Seah; Zain H Charface; Zarif Khan; Wasim Khan; Niel Kang; Joel Thomas Kirk Melton; Andrew W McCaskie; Stephen M McDonnell
Journal:  Bone Jt Open       Date:  2021-04

7.  National operating volume for primary hip and knee arthroplasty in the COVID-19 era: a study utilizing the Scottish arthroplasty project dataset.

Authors:  Liam Z Yapp; Jon V Clarke; Matthew Moran; A Hamish R W Simpson; Chloe E H Scott
Journal:  Bone Jt Open       Date:  2021-03

8.  Higher 90-Day Mortality after Surgery for Hip Fractures in Patients with COVID-19: A Case-Control Study from a Single Center in Italy.

Authors:  Alberto Grassi; Luca Andriolo; Davide Golinelli; Dario Tedesco; Simona Rosa; Pasquale Gramegna; Jacopo Ciaffi; Riccardo Meliconi; Maria Paola Landini; Giuseppe Filardo; Maria Pia Fantini; Stefano Zaffagnini
Journal:  Int J Environ Res Public Health       Date:  2021-05-13       Impact factor: 3.390

Review 9.  Surgery for pancreatic tumors in the midst of COVID-19 pandemic.

Authors:  Hiroyuki Kato; Yukio Asano; Satoshi Arakawa; Masahiro Ito; Norihiko Kawabe; Masahiro Shimura; Chihiro Hayashi; Takayuki Ochi; Hironobu Yasuoka; Takahiko Higashiguchi; Yuka Kondo; Hidetoshi Nagata; Akihiko Horiguchi
Journal:  World J Clin Cases       Date:  2021-06-26       Impact factor: 1.337

10.  A COVID-19 Pivot Plan to Resume Elective Surgeries at the Hartford Healthcare Connecticut Orthopaedic Institute.

Authors:  Swaroopa Vaidya; Daniel Berluti; John F Irving; Gerard Girasole; John D McCallum; Leonard Kolstad; Tara McLaughlin
Journal:  Cureus       Date:  2021-05-17
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