Literature DB >> 33248142

Lichen Sclerosus and Phimosis - Discrepancies Between Clinical and Pathological Diagnosis and Its Consequences.

Mateusz Czajkowski1, Anton Żawrocki2, Katarzyna Czajkowska3, Jakub Kłącz4, Małgorzata Sokołowska-Wojdyło3, Wojciech Biernat2, Marcin Matuszewski4.   

Abstract

OBJECTIVE: To assess the accuracy of clinical diagnoses and the true incidence of lichen sclerosus (LS) in patients with phimosis.
MATERIALS AND METHODS: The 92 adult male patients who were qualified for circumcision due to phimosis, were included in the study. The patients were diagnosed clinically by a urologist and dermatologist before the surgical procedure. After the circumcision, the resected foreskins were examined by 2 independent uropathologists.
RESULTS: Preoperative clinical diagnosis of LS was established in 54 patients (58.7%); healthy-looking skin in 26 (28.3%) and other penile diseases in 12 (13.1%) patients. After histopathological examination, the diagnosis of LS was established in 62 patients (67.4%), but only in 44 patients with previous LS clinical diagnosis. LS was histopathologically confirmed in 18 other patients with clinically diagnosed healthy skin (n = 17) or lichen planus (n = 1). Healthy skin was histopathologically confirmed in 10 cases in patients diagnosed clinically before as LS. Other 15 histopathological diagnoses were Zoon balanitis (n = 3), nonspecific balanitis (n = 5), lichen planus (n = 1), psoriasis (n = 1), invasive penile cancer (n = 3), Bowen's disease (n = 1), penile intraepithelial neoplasia 2 usual type (n = 1).
CONCLUSION: LS has been revealed as the most common histopathological diagnosis in patients undergoing circumcision in our study. Histopathological examination seems to be necessary to exclude this disease.
Copyright © 2020 Elsevier Inc. All rights reserved.

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Year:  2020        PMID: 33248142     DOI: 10.1016/j.urology.2020.11.027

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


  4 in total

1.  Prevalence and sequelae of penile lichen sclerosus in males presenting for circumcision in regional Australia: a multicentre retrospective cohort study.

Authors:  Michael Kwok; Nathan Shugg; Amila Siriwardana; Ross Calopedos; Katherine Richards; Sanjeev Bandi; John Hempenstall; Prem Rashid; Devang Desai
Journal:  Transl Androl Urol       Date:  2022-06

2.  Can circumcision be avoided in adult male with phimosis? Results of the PhimoStopTM prospective trial.

Authors:  Marco Carilli; Anastasios D Asimakopoulos; Serena Pastore; Stefano Germani; Luca Orecchia; Enrico Finazzi Agrò; Roberto Miano
Journal:  Transl Androl Urol       Date:  2021-11

3.  Have been the incidence and consequences of penile lichen sclerosus still underestimated?

Authors:  Mateusz Czajkowski; Katarzyna Czajkowska; Małgorzata Sokołowska-Wojdyło; Marcin Matuszewski
Journal:  Transl Androl Urol       Date:  2022-08

4.  The role of occlusion and micro-incontinence in the pathogenesis of penile lichen sclerosus: an observational study of pro-inflammatory cytokines' gene expression.

Authors:  M Czajkowski; P Wierzbicki; A Kotulak-Chrząszcz; K Czajkowska; M Bolcewicz; J Kłącz; K Kreft; A Lewandowska; B Nedoszytko; M Sokołowska-Wojdyło; Z Kmieć; L Kalinowski; R J Nowicki; M Matuszewski
Journal:  Int Urol Nephrol       Date:  2022-02-01       Impact factor: 2.370

  4 in total

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