Literature DB >> 33247647

COVID-19 and Tuberculosis: A Meeting of Two Pandemics!

Udita Gupta1, Anupam Prakash2, Sonali Sachdeva1, Ghan Shyam Pangtey2, Akshita Khosla1, Ramesh Aggarwal2, Ritika Sud2, Shubha Laxmi Margekar2.   

Abstract

Coronavirus disease 2019 (COVID-19), causes serious respiratory illness manifesting as pneumonia, adult respiratory distress syndrome and respiratory failure. Amidst the rising number of cases and deaths, it is imperative to not forget Tuberculosis (TB) which is another pandemic existing since centuries. There could be dire consequences for tuberculosis patients globally especially in low and middle income countries with a high burden of disease and overwhelmed health care systems. Tuberculosis is still the leading infectious killer worldwide, and therefore, it is crucial to reflect on the interaction between the two diseases. Evidence suggests that both COVID-19 and tuberculosis have a synergistic relationship, boosting detrimental effect of each other, disrupting existing health care models, and also worsening the clinical outcomes in terms of morbidity and mortality. This review aims to draw attention towards this pertinent clinical issue, and tries to unravel the intricate relationship between COVID-19 and tuberculosis, as also the role of BCG vaccination to combat the COVID-19 pandemic. © Journal of the Association of Physicians of India 2011.

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Year:  2020        PMID: 33247647

Source DB:  PubMed          Journal:  J Assoc Physicians India        ISSN: 0004-5772


  3 in total

1.  Relationship of SARS-CoV-2-specific CD4 response to COVID-19 severity and impact of HIV-1 and tuberculosis coinfection.

Authors:  Catherine Riou; Elsa du Bruyn; Cari Stek; Remy Daroowala; Rene T Goliath; Fatima Abrahams; Qonita Said-Hartley; Brian W Allwood; Nei-Yuan Hsiao; Katalin A Wilkinson; Cecilia S Lindestam Arlehamn; Alessandro Sette; Sean Wasserman; Robert J Wilkinson
Journal:  J Clin Invest       Date:  2021-06-15       Impact factor: 14.808

2.  Repurposing Based Identification of Novel Inhibitors against MmpS5-MmpL5 Efflux Pump of Mycobacterium smegmatis: A Combined In Silico and In Vitro Study.

Authors:  Mohd Shahbaaz; Dmitry A Maslov; Aleksey A Vatlin; Valery N Danilenko; Maria Grishina; Alan Christoffels
Journal:  Biomedicines       Date:  2022-01-31

3.  Tuberculosis in Poland: Epidemiological and Molecular Analysis during the COVID-19 Pandemic.

Authors:  Dagmara Borkowska-Tatar; Anna Zabost; Monika Kozińska; Ewa Augustynowicz-Kopeć
Journal:  Diagnostics (Basel)       Date:  2022-08-03
  3 in total

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