Zeyu Zhang1, Fada Xia1, Wenlong Wang1, Bo Jiang1, Lei Yao1, Yun Huang2, Xinying Li1. 1. Department of Thyroid Surgery, Xiangya Hospital, Central South University, Changsha, China. 2. Department of General Surgery, Xiangya Hospital, Central South University, Changsha, China.
Abstract
BACKGROUND: Currently, no randomized controlled trial has been performed to investigate the safety profiles, economic benefit and mental health of ambulatory thyroidectomy in patients with papillary thyroid carcinoma (PTC). METHODS:Patients diagnosed with PTC were enrolled in this study and were randomly assigned to ambulatory group and control group. The safety profiles, economic benefit and mental health were investigated. RESULTS:Four hundred and eleven patients completed the study. There was no significant difference in demographic or tumor index. The incidence of complications was not significantly different (P = .631). The economic cost was significantly lower (P < .001) and hospitalization was significantly shorter (P < .001) in ambulatory group. No significant difference was shown in depression (P = .758) and stress disorder (P = .390). However, the ambulatory group showed a higher point of anxiety (P < .001). CONCLUSION: The ambulatory thyroidectomy is safe in patients with PTC, with significant benefits of economic cost and hospitalization.
RCT Entities:
BACKGROUND: Currently, no randomized controlled trial has been performed to investigate the safety profiles, economic benefit and mental health of ambulatory thyroidectomy in patients with papillary thyroid carcinoma (PTC). METHODS:Patients diagnosed with PTC were enrolled in this study and were randomly assigned to ambulatory group and control group. The safety profiles, economic benefit and mental health were investigated. RESULTS: Four hundred and eleven patients completed the study. There was no significant difference in demographic or tumor index. The incidence of complications was not significantly different (P = .631). The economic cost was significantly lower (P < .001) and hospitalization was significantly shorter (P < .001) in ambulatory group. No significant difference was shown in depression (P = .758) and stress disorder (P = .390). However, the ambulatory group showed a higher point of anxiety (P < .001). CONCLUSION: The ambulatory thyroidectomy is safe in patients with PTC, with significant benefits of economic cost and hospitalization.