Rui Li1, Cong Li1, Zhifeng Mao2, Qiao Huang3, Yaqing Shu1, Yanyu Chang1, Jingqi Wang1, Yuge Wang1, Wei Qiu4. 1. Multiple Sclerosis Center, Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Guangzhou, 510630, Guangdong Province, China. 2. KingMed College of Laboratory Medicine, Guangzhou Medical University, Guangzhou, Guangdong, China. 3. The Second People's Hospital of Zhaoqing, Zhaoqing, China. 4. Multiple Sclerosis Center, Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Guangzhou, 510630, Guangdong Province, China. qiuwei120@vip.163.com.
Abstract
BACKGROUND: Clinical data on male neuromyelitis optica spectrum (NMO) patients remain limited to date. OBJECTIVE: To analyze clinical characteristics, therapeutic responses, and outcomes in Chinese male NMOSD patients. METHODS: We retrospectively assessed clinical, demographic, treatment, and outcome data of male patients with NMOSD. RESULTS: We identified 52 male patients among 471 NMOSD patients. Male patients had more frequent optic neuritis (ON) attacks and less frequent myelitis than female patients. No-remission rates of high-dose intravenous steroid therapy were higher in male patients than in female patients. CONCLUSION: Male NMOSD patients had different clinical characteristics and worse response to high-dose intravenous steroid therapy than female patients.
BACKGROUND: Clinical data on male neuromyelitis optica spectrum (NMO) patients remain limited to date. OBJECTIVE: To analyze clinical characteristics, therapeutic responses, and outcomes in Chinese male NMOSD patients. METHODS: We retrospectively assessed clinical, demographic, treatment, and outcome data of male patients with NMOSD. RESULTS: We identified 52 male patients among 471 NMOSD patients. Male patients had more frequent optic neuritis (ON) attacks and less frequent myelitis than female patients. No-remission rates of high-dose intravenous steroid therapy were higher in male patients than in female patients. CONCLUSION: Male NMOSD patients had different clinical characteristics and worse response to high-dose intravenous steroid therapy than female patients.
Authors: Dean M Wingerchuk; Brenda Banwell; Jeffrey L Bennett; Philippe Cabre; William Carroll; Tanuja Chitnis; Jérôme de Seze; Kazuo Fujihara; Benjamin Greenberg; Anu Jacob; Sven Jarius; Marco Lana-Peixoto; Michael Levy; Jack H Simon; Silvia Tenembaum; Anthony L Traboulsee; Patrick Waters; Kay E Wellik; Brian G Weinshenker Journal: Neurology Date: 2015-06-19 Impact factor: 9.910