Literature DB >> 33241711

The clinical phenotype of bronchiectasis and its clinical guiding implications.

Li Gao1, Ke-Ru Qin2, Ting Li1, Hai-Long Wang2, Min Pang1.   

Abstract

Bronchiectasis is a chronic airway disease with abnormal and persistent bronchial dilatation caused by a variety of reasons. In recent years, numerous reports have shown that bronchiectasis is heterogeneous, the clinical characteristics of patients with different phenotypes are different, and the efficacy of a treatment regimen may vary greatly in patients with different bronchiectasis phenotypes. This paper summarizes the current clinical phenotypic classification of bronchiectasis from the perspective of etiology, microbiology, and the frequency of acute exacerbation, and cluster analysis was used to determine new clinical phenotypes and their statistical and clinical significance. Different tools for assessing disease severity yield different outcomes. This article summarizes the research progress in the above areas, hoping to provide a more comprehensive understanding of the disease.

Entities:  

Keywords:  Bronchiectasis; cluster analysis; deterioration frequency; etiology; microbiology; phenotype

Mesh:

Year:  2020        PMID: 33241711      PMCID: PMC7876648          DOI: 10.1177/1535370220972324

Source DB:  PubMed          Journal:  Exp Biol Med (Maywood)        ISSN: 1535-3699


  42 in total

Review 1.  Inhaled antibiotics for stable non-cystic fibrosis bronchiectasis: a systematic review.

Authors:  Alessandra Monteiro Brodt; Elizabeth Stovold; Linjie Zhang
Journal:  Eur Respir J       Date:  2014-06-12       Impact factor: 16.671

2.  Pulmonary immunity to Pseudomonas aeruginosa in intestinally immunized rats roles of alveolar macrophages, tumor necrosis factor alpha, and interleukin-1 alpha.

Authors:  A Buret; M L Dunkley; G Pang; R L Clancy; A W Cripps
Journal:  Infect Immun       Date:  1994-12       Impact factor: 3.441

3.  The Multiple Faces of Non-Cystic Fibrosis Bronchiectasis. A Cluster Analysis Approach.

Authors:  Miguel Á Martínez-García; Montserrat Vendrell; Rosa Girón; Luis Máiz-Carro; David de la Rosa Carrillo; Javier de Gracia; Casilda Olveira
Journal:  Ann Am Thorac Soc       Date:  2016-09

4.  Pseudomonas aeruginosa in patients hospitalised for COPD exacerbation: a prospective study.

Authors:  C Garcia-Vidal; P Almagro; V Romaní; M Rodríguez-Carballeira; E Cuchi; L Canales; D Blasco; J L Heredia; J Garau
Journal:  Eur Respir J       Date:  2009-04-22       Impact factor: 16.671

5.  Impact of Radiographic Bronchiectasis in COPD.

Authors:  Lei Shi; Fengxian Wei; Tiantian Ma; Weixin Zhou; Min Li; Yixin Wan
Journal:  Respir Care       Date:  2020-04-07       Impact factor: 2.258

6.  Phenotyping Adults with Non-Cystic Fibrosis Bronchiectasis: A 10-Year Cohort Study in a French Regional University Hospital Center.

Authors:  Matthieu Buscot; Héloïse Pottier; Charles-Hugo Marquette; Sylvie Leroy
Journal:  Respiration       Date:  2016-06-24       Impact factor: 3.580

7.  Determining emphysema in adult patients with COPD-bronchiectasis overlap using a novel spirometric parameter: area under the forced expiratory flow-volume loop.

Authors:  Celal Satici; Burcu Arpinar Yigitbas; Mustafa Asim Demirkol
Journal:  Expert Rev Respir Med       Date:  2020-05-18       Impact factor: 3.772

8.  The existence of bronchiectasis predicts worse prognosis in patients with COPD.

Authors:  Bei Mao; Hai-Wen Lu; Man-Hui Li; Li-Chao Fan; Jia-Wei Yang; Xia-Yi Miao; Jin-Fu Xu
Journal:  Sci Rep       Date:  2015-06-16       Impact factor: 4.379

Review 9.  Bronchiectasis in COPD patients: more than a comorbidity?

Authors:  Miguel Angel Martinez-Garcia; Marc Miravitlles
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2017-05-11

Review 10.  Vaccination against respiratory Pseudomonas aeruginosa infection.

Authors:  Keith Grimwood; Jennelle M Kyd; Suzzanne J Owen; Helen M Massa; Allan W Cripps
Journal:  Hum Vaccin Immunother       Date:  2014-11-01       Impact factor: 3.452

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