| Literature DB >> 33241711 |
Li Gao1, Ke-Ru Qin2, Ting Li1, Hai-Long Wang2, Min Pang1.
Abstract
Bronchiectasis is a chronic airway disease with abnormal and persistent bronchial dilatation caused by a variety of reasons. In recent years, numerous reports have shown that bronchiectasis is heterogeneous, the clinical characteristics of patients with different phenotypes are different, and the efficacy of a treatment regimen may vary greatly in patients with different bronchiectasis phenotypes. This paper summarizes the current clinical phenotypic classification of bronchiectasis from the perspective of etiology, microbiology, and the frequency of acute exacerbation, and cluster analysis was used to determine new clinical phenotypes and their statistical and clinical significance. Different tools for assessing disease severity yield different outcomes. This article summarizes the research progress in the above areas, hoping to provide a more comprehensive understanding of the disease.Entities:
Keywords: Bronchiectasis; cluster analysis; deterioration frequency; etiology; microbiology; phenotype
Mesh:
Year: 2020 PMID: 33241711 PMCID: PMC7876648 DOI: 10.1177/1535370220972324
Source DB: PubMed Journal: Exp Biol Med (Maywood) ISSN: 1535-3699