Literature DB >> 33241106

The discovery of AVIL as a bona fide oncogene in glioblastoma.

Zhongqiu Xie1, Hui Li1,2.   

Abstract

Our work in rhabdomyosarcoma led us to the discovery of a novel oncogene, Advillin (AVIL) in glioblastoma. Multiple lines of evidence support that AVIL is an Achilles heel of glioblastoma, with its specific targeting potentially an effective treatment approach for the disease. A new signaling axis was also established.
© 2020 Taylor & Francis Group, LLC.

Entities:  

Keywords:  AVIL; glioblastoma; oncogene addiction; rhabdomyosarcoma

Year:  2020        PMID： 33241106      PMCID： PMC7671026          DOI： 10.1080/23723556.2020.1804309

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  6 in total

1.  The forkhead transcription factor FOXM1 controls cell cycle-dependent gene expression through an atypical chromatin binding mechanism.

Authors:  Xi Chen; Gerd A Müller; Marianne Quaas; Martin Fischer; Namshik Han; Benjamin Stutchbury; Andrew D Sharrocks; Kurt Engeland
Journal:  Mol Cell Biol       Date:  2012-10-29       Impact factor: 4.272

2.  Fusion transcriptome profiling provides insights into alveolar rhabdomyosarcoma.

Authors:  Zhongqiu Xie; Mihaela Babiceanu; Shailesh Kumar; Yuemeng Jia; Fujun Qin; Frederic G Barr; Hui Li
Journal:  Proc Natl Acad Sci U S A       Date:  2016-10-31       Impact factor: 11.205

3.  MicroRNA-125b suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2.

Authors:  Linhui Liang; Chun-Ming Wong; Qiao Ying; Dorothy Ngo-Yin Fan; Shenglin Huang; Jie Ding; Jian Yao; Mingxia Yan; Jinjun Li; Ming Yao; Irene Oi-Lin Ng; Xianghuo He
Journal:  Hepatology       Date:  2010-11       Impact factor: 17.425

4.  A chimeric RNA characteristic of rhabdomyosarcoma in normal myogenesis process.

Authors:  Huiling Yuan; Fujun Qin; Mercedeh Movassagh; Hong Park; Wendy Golden; Zhongqiu Xie; Peng Zhang; Jeffrey Sklar; Hui Li
Journal:  Cancer Discov       Date:  2013-10-02       Impact factor: 39.397

5.  The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data.

Authors:  Ethan Cerami; Jianjiong Gao; Ugur Dogrusoz; Benjamin E Gross; Selcuk Onur Sumer; Bülent Arman Aksoy; Anders Jacobsen; Caitlin J Byrne; Michael L Heuer; Erik Larsson; Yevgeniy Antipin; Boris Reva; Arthur P Goldberg; Chris Sander; Nikolaus Schultz
Journal:  Cancer Discov       Date:  2012-05       Impact factor: 39.397

Review 6.  Sphingolipid organization in biomembranes: what physical studies of model membranes reveal.

Authors:  R E Brown
Journal:  J Cell Sci       Date:  1998-01       Impact factor: 5.285
  6 in total

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