Literature DB >> 33238055

Reconstruction after periacetabular tumor resection with Lumic® endoprosthesis: What are the midterm results?

Bulent Erol1, Omer Sofulu1, Evrim Sirin1, Fevzi Saglam1, Omer Buyuktopcu1.   

Abstract

INTRODUCTION: This study aimed to analyze the midterm outcomes of LUMiC® endoprosthetic reconstruction following periacetabular resection of primary bone sarcomas and carcinoma metastases. PATIENTS AND METHODS: We retrospectively reviewed the charts of 21 patients (11 male [52.3%], 10 female [47.6%]; mean age 47 ± 16 years) for whom a LUMiC® endoprosthesis (Implantcast) was used to reconstruct a periacetabular defect after internal hemipelvectomy. The tumor was pathologically diagnosed as Ewing's sarcoma in six (28.5%), chondrosarcoma in 10 (47.6%), and bone metastasis from carcinoma in five (23.8%) patients.
RESULTS: The median follow-up of patients was 57.8 months (95% confidence interval: 51.9-63.7). The implant survival rate at 1, 2, and 5 years were 95.2%, 85.7%, and 80.9%, respectively. The overall complication rate was 33.3% (n = 7). Four (19%) complications resulted in reconstruction failure. Total reoperation rate was 28.5% (n = 6). The complications were soft tissue failure/dislocation in two patients, aseptic loosening in one, infection in two, and local recurrence in two. At the time of study, seven patients were alive with no evidence of disease, seven were alive with disease, and seven died of disease. The 5-year overall survival rate and local recurrence-free survival rates were 67% and 76%, respectively. The median Musculoskeletal Tumor Society score at final follow-up was 70% (range: 50%-86.6%).
CONCLUSION: We conclude that LUMiC® endoprosthesis provides good functional outcomes and a durable reconstruct. Even though this reconstruction method presents some complications, it provides a stable pelvis in the management of periacetabular malignant tumors.
© 2020 Wiley Periodicals LLC.

Entities:  

Keywords:  LUMiC® endoprosthesis; endoprosthetic reconstruction; metastasis; periacetabular tumor; sarcoma

Year:  2020        PMID: 33238055     DOI: 10.1002/jso.26318

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN: 0022-4790            Impact factor:   3.454


  4 in total

Review 1.  The iliac stemmed cup in reconstruction of the acetabular defects secondary to tumor resection: a systematic review of literature.

Authors:  Carmine Zoccali; Giuseppe Giannicola; Giovanni Zoccali; Elisa Checcucci; Alessandra Scotto di Uccio; Dario Attala; Ciro Villani
Journal:  Arch Orthop Trauma Surg       Date:  2022-10-01       Impact factor: 2.928

Review 2.  Surgical Treatment of Bone Sarcoma.

Authors:  Felix Bläsius; Heide Delbrück; Frank Hildebrand; Ulf Krister Hofmann
Journal:  Cancers (Basel)       Date:  2022-05-29       Impact factor: 6.575

Review 3.  Endoprosthetic Reconstruction in Ewing's Sarcoma Patients: A Systematic Review of Postoperative Complications and Functional Outcomes.

Authors:  Jude Abu El Afieh; Marena Gray; Matthew Seah; Wasim Khan
Journal:  J Clin Med       Date:  2022-08-08       Impact factor: 4.964

4.  Emerging Concepts in the Surgical Management of Peri-Acetabular Metastatic Bone Disease.

Authors:  Aaron Gazendam; Daniel Axelrod; David Wilson; Michelle Ghert
Journal:  Curr Oncol       Date:  2021-07-17       Impact factor: 3.677

  4 in total

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