Literature DB >> 33237663

Treatment of SARS-CoV-2 pneumonia with favipiravir: early results from the Ege University cohort, Turkey

Hüseyin Aytaç Erdem1, Pervin Ekren Korkma2, Derya Çağlayan1, Meltem Işıkgöz Taşbakan1, Tansu Yamazhan1, Mehmet Sezai Taşbakan2, Abdullah Sayıner2, Deniz Gökengin1.   

Abstract

Background/aim: The aim of this descriptive article is to share the experience in Ege University, Turkey with favipiravir in the treatment of severe SARS-CoV-2 pneumonia. Materials and methods: This retrospective descriptive study included patients diagnosed with COVID-19 who presented with or developed severe pneumonia.
Results: Forty patients who completed a full course (at least 5 days) of favipiravir were included in the study. At baseline, 30 (75%) patients required treatment for respiratory distress. Thirty-three patients (82.5%) were discharged from the hospital with full recovery, 6 patients (15%) died and 1 case (2.5%) was still at the intensive care unit (ICU) when this paper was written.
Conclusion: This study provides relevant information for the treatment of COVID-19, suggesting that favipiravir was associated with significant clinical and laboratory improvements in the majority of the patients, is a safe drug with no serious side effects and would merit further investigation. This work is licensed under a Creative Commons Attribution 4.0 International License.

Entities:  

Keywords:  antiviral therapy; coronavirus; favipiravir; pandemic; SARS-CoV-2; COVID-19; antiviral therapy

Mesh:

Substances:

Year:  2021        PMID: 33237663     DOI: 10.3906/sag-2008-33

Source DB:  PubMed          Journal:  Turk J Med Sci        ISSN: 1300-0144            Impact factor:   0.973


  5 in total

1.  Antibiotic use and Influencing Factors Among Hospitalized Patients with COVID-19: A Multicenter Point-Prevalence Study from Turkey

Authors:  İrfan Şencan; Yasemin Çağ; Oğuz Karabay; Behice Kurtaran; Ertuğrul Güçlü; Aziz Öğütlü; Zehra Demirbaş; Dilek Bulut; Gülden Eser Karlıdağ; Merve Sefa Sayar; Ezgi Gizem Şibar; Oya Özlem Eren Kutsoylu; Gülnur Kul; Serpil Erol; Begüm Bektaş; Tülay Ünver Ulusoy; Semanur Kuzi; Meltem Tasbakan; Özge Yiğit; Nurgül Ceran; Ayşe Seza İnal; Pınar Ergen; Tansu Yamazhan; Hanife Uzar; Canan Ağalar
Journal:  Balkan Med J       Date:  2022-05-24       Impact factor: 3.570

Review 2.  Achievements of the COVID-19 Turkey Platform in vaccine and drug development with an approach of "co-creation and succeeding together".

Authors:  Hasan Mandal
Journal:  Turk J Med Sci       Date:  2021-12-17       Impact factor: 0.973

3.  Efficacy and safety of favipiravir plus interferon-beta versus lopinavir/ritonavir plus interferon-beta in moderately ill patients with COVID-19: A randomized clinical trial.

Authors:  Mehdi Hassaniazad; Hossein Farshidi; Abdollah Gharibzadeh; Ali Bazram; Elham Khalili; Afsaneh Noormandi; Mohammad Fathalipour
Journal:  J Med Virol       Date:  2022-03-24       Impact factor: 20.693

4.  The safety profile of favipiravir in COVID-19 patients with severe renal impairment.

Authors:  Selim Gök; Ömer Faruk Bahçecioğlu; Mefküre Durmuş; Zeynep Ülkü Gün; Yasemin Ersoy; Zeynep Ayfer Aytemur; Özkan Ulutaş
Journal:  Int J Clin Pract       Date:  2021-10-10       Impact factor: 3.149

5.  The efficacy and safety of Favipiravir in treatment of COVID-19: a systematic review and meta-analysis of clinical trials.

Authors:  Soheil Hassanipour; Morteza Arab-Zozani; Bahman Amani; Forough Heidarzad; Mohammad Fathalipour; Rudolph Martinez-de-Hoyo
Journal:  Sci Rep       Date:  2021-05-26       Impact factor: 4.379

  5 in total

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