Designer receptor inhibition suggests mechanism for monkey Theory of Mind.

Theory of Mind (ToM) is a critical component of human social cognition that has not been found reliably in other primates, especially monkeys. Hayashi et al. (Cell Reports, 30, 4433-4444, 2020) used newly developed behavioral techniques to detect evidence for ToM in Japanese macaque monkeys and employed sophisticated neurobiological manipulations to implicate the medial prefrontal cortex is this capacity.