Literature DB >> 33227587

Contributing to a better understanding of infectious respiratory diseases in Mozambique.

Tufária Mussá1.   

Abstract

Entities:  

Year:  2020        PMID: 33227587      PMCID: PMC7691743          DOI: 10.1016/j.ebiom.2020.103128

Source DB:  PubMed          Journal:  EBioMedicine        ISSN: 2352-3964            Impact factor:   8.143


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Infectious respiratory diseases are one of the main causes of mortality in children [1]. Globally, we have seen a reduction of the mortality rates in children younger than 5 years since the ‘90s thanks to an increase in vaccine coverage and reductions in household air pollution [2]. However, this scenario is different in Sub-Saharan Africa settings, where the universal health coverage effective coverage index is lower than 25 (on a 1 to 100 scale) and vaccine coverage remains challenging [3,4]. Indeed, one of the GAVI, the Vaccine Alliance strategic goals for the upcoming 25 years is to increase equity in immunisation uptake by strengthening health care systems [5]. Besides the limited access to competing funds, a big challenge that LMIC researchers working on paediatric infectious respiratory diseases face is the amount of overall demand from a weak health care system. This is particularly striking in this era of multidrug resistant-tuberculosis, COVID-19, air pollution, and malnutrition which affect a population in demographic transition with a variety of other underlying clinical conditions. The end result is that health care professionals are stretched with clinical duties without sufficient time to dedicate to research or training. In addition, many African public hospitals face chronic staff and consumables shortages, creating a challenge to adhere to research protocols and compromising the completeness of research plans. Although most research projects result from triangular collaborations, it is important that African researchers participate as soon as initial discussions of proposals and ideas take place. This would be fundamental to plan and define the needed financial, infrastructure and human resources. Research projects aligned with global or national health agendas ultimately fuel further research work and collaborations, allowing the absorption of the trained staff, and contributing to capacity building. On the other side, regional networks are also fundamental, as they represent a mean by which African researchers could easily congregate people with common interests and apply for funds, creating regional capacity to continue research and training. Overall, as much as an investment in research is needed, it is of extreme importance to strengthen the health care systems to allow continued training of health care professionals in Africa.

Contributors

TM has done the research and wrote the letter.

Declaration of Competing Interest

Author declares no conflict of interest.
  4 in total

Review 1.  Paediatric respiratory infections.

Authors:  Mark L Everard
Journal:  Eur Respir Rev       Date:  2016-03

Review 2.  Interventions to increase the distribution of vaccines in Sub-Saharan Africa: a scoping review.

Authors:  Marius Zambou Vouking; Christelle Monique Angoula Mengue; Saidu Yauba; Jean Marie Edengue; Modibo Dicko; Hamadou Modibo Dicko; Charles Shey Wiysonge
Journal:  Pan Afr Med J       Date:  2019-01-09

3.  Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.

Authors: 
Journal:  Lancet       Date:  2020-08-27       Impact factor: 202.731

4.  Quantifying risks and interventions that have affected the burden of lower respiratory infections among children younger than 5 years: an analysis for the Global Burden of Disease Study 2017.

Authors: 
Journal:  Lancet Infect Dis       Date:  2019-10-31       Impact factor: 25.071

  4 in total

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