| Literature DB >> 33223079 |
Cynthia Bodkin1, Robert M Pascuzzi2.
Abstract
Myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) are the most common disorders of neuromuscular transmission in clinical practice. Disorders of the neuromuscular junction (NMJ) are characterized by fluctuating and fatigable weakness and include autoimmune, toxic, and genetic conditions. Adults with NMJ disorders are most often antibody mediated, with MG being the most common, having a prevalence of approximately 1 in 10,000, and with women being affected about twice as often as men. This article focuses on advances in management of autoimmune MG and LEMS.Entities:
Keywords: Complement inhibitor; Lambert Eaton myasthenic syndrome; Myasthenia gravis; Thymectomy; Weakness
Year: 2020 PMID: 33223079 DOI: 10.1016/j.ncl.2020.09.007
Source DB: PubMed Journal: Neurol Clin ISSN: 0733-8619 Impact factor: 3.806