Literature DB >> 3322004

Chromosome anomalies as predictors of recurrence risk for spontaneous abortion.

N E Morton1, D Chiu, C Holland, P A Jacobs, D Pettay.   

Abstract

Reproductive histories and chromosomes of spontaneous abortions were studied by segregation analysis in 1890 sibships ascertained through a cytogenetically studied abortion. Normal karyotypes are associated with recurrent abortion. Among abnormal karyotypes, trisomy has an elevated recurrence risk even after adjustment through a liability indicator for maternal age. Possible mechanisms and conflicting evidence in the literature on trisomy are discussed. None of these differences in recurrence risk is large enough to play a significant numerical role in genetic counseling.

Entities:  

Mesh：

Year:  1987        PMID： 3322004     DOI： 10.1002/ajmg.1320280213

Source DB:  PubMed          Journal:  Am J Med Genet        ISSN： 0148-7299


  8 in total

1.  Cytogenetic analysis of 750 spontaneous abortions with the direct-preparation method of chorionic villi and its implications for studying genetic causes of pregnancy wastage.

Authors:  B Eiben; I Bartels; S Bähr-Porsch; S Borgmann; G Gatz; G Gellert; R Goebel; W Hammans; M Hentemann; R Osmers
Journal:  Am J Hum Genet       Date:  1990-10       Impact factor: 11.025

2.  Recurrences of trisomy 18 and trisomy 13 after trisomy 21.

Authors:  D R FitzPatrick; E Boyd
Journal:  Hum Genet       Date:  1989-06       Impact factor: 4.132

Review 3.  Intravenous immunoglobulin and recurrent pregnancy loss.

Authors:  Howard J A Carp; Tal Sapir; Yehuda Shoenfeld
Journal:  Clin Rev Allergy Immunol       Date:  2005-12       Impact factor: 8.667

4.  Invasive prenatal testing.

Authors:  A Hunter
Journal:  Can Fam Physician       Date:  1988-04       Impact factor: 3.275

5.  The predictive value of chorionic villus histology for identifying chromosomally normal and abnormal spontaneous abortions.

Authors:  C Minguillon; B Eiben; S Bähr-Porsch; M Vogel; I Hansmann
Journal:  Hum Genet       Date:  1989-07       Impact factor: 4.132

6.  The origin of abnormalities in recurrent aneuploidy/polyploidy.

Authors:  W P Robinson; D E McFadden; M D Stephenson
Journal:  Am J Hum Genet       Date:  2001-10-23       Impact factor: 11.025

7.  Skewed X-chromosome inactivation is associated with trisomy in women ascertained on the basis of recurrent spontaneous abortion or chromosomally abnormal pregnancies.

Authors:  C L Beever; M D Stephenson; M S Peñaherrera; R H Jiang; D K Kalousek; M Hayden; L Field; C J Brown; W P Robinson
Journal:  Am J Hum Genet       Date:  2002-12-20       Impact factor: 11.025

Review 8.  1(st) trimester miscarriage: four decades of study.

Authors:  Kathy Hardy; Philip John Hardy
Journal:  Transl Pediatr       Date:  2015-04
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.