Literature DB >> 33217719

Paraneoplastic cerebellar degeneration associated with anti-protein kinase Cgamma antibodies in a Chinese patient.

Haitao Ren1, Dachun Zhao2, Xiaolu Xu1, Yingmai Yang1, Siyuan Fan1, Wenhan Li3, Hongzhi Guan4.   

Abstract

Anti-protein kinase Cgamma (anti-PKCγ) antibodies are rare onconeural antibodies associated with paraneoplastic cerebellar degeneration (PCD). To date, only two patients with PCD and anti-PKCγ antibodies have been reported. Here, we report a Chinese patient with PCD and anti-PKCγ antibodies. Screening for tumor revealed lymphoepithelial carcinoma in tonsil. The patient's symptoms improved gradually after radiotherapy for the lymphoepithelial carcinoma and intravenous immunoglobulin immunotherapy.
Copyright © 2020. Published by Elsevier B.V.

Entities:  

Keywords:  Anti-protein kinase Cgamma antibodies; Ataxia; Paraneoplastic cerebellar degeneration

Year:  2020        PMID: 33217719     DOI: 10.1016/j.jneuroim.2020.577408

Source DB:  PubMed          Journal:  J Neuroimmunol        ISSN: 0165-5728            Impact factor:   3.478


  1 in total

1.  Evaluation of the Updated Diagnostic Criteria for Paraneoplastic Neurologic Syndromes in China.

Authors:  Meng-Ting Cai; Song Qiao; Qi-Lun Lai; Yang Zheng; Fan Yang; Gao-Li Fang; Chun-Hong Shen; Yin-Xi Zhang; Mei-Ping Ding
Journal:  Front Immunol       Date:  2022-01-31       Impact factor: 7.561

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.