| Literature DB >> 33217409 |
Chiara Piazzola1, Lorenzo Tamellini2, Raúl Tempone3.
Abstract
We provide an overview of the methods that can be used for prediction under uncertainty and data fitting of dynamical systems, and of the fundamental challenges that arise in this context. The focus is on SIR-like models, that are being commonly used when attempting to predict the trend of the COVID-19 pandemic. In particular, we raise a warning flag about identifiability of the parameters of SIR-like models; often, it might be hard to infer the correct values of the parameters from data, even for very simple models, making it non-trivial to use these models for meaningful predictions. Most of the points that we touch upon are actually generally valid for inverse problems in more general setups.Entities:
Keywords: Bayesian inversion; Dynamical systems; Fisher approximation; Mathematical epidemiology; Model identifiability; Uncertainty Quantification
Mesh:
Year: 2020 PMID: 33217409 DOI: 10.1016/j.mbs.2020.108514
Source DB: PubMed Journal: Math Biosci ISSN: 0025-5564 Impact factor: 2.144