Joel B Epstein1, David R Dean2, Stephen T Sonis3,4. 1. City of Hope Comprehensive Cancer Center, Duarte CA and Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical System, Los Angeles, CA, USA. jepstein@coh.org. 2. Seattle Cancer Care Alliance/University of Washington, Seattle, WA, USA. 3. Brigham and Women's Hospital and the Dana-Farber Cancer Institute, Boston, MA, USA. 4. Biomodels, LLC and Primary Endpoint Solutions, Waltham, MA, USA.