Literature DB >> 3321208

Cellular immunity in the joints of patients with rheumatoid arthritis and other forms of chronic synovitis.

G S Firestein1, V Tsai, N J Zvaifler.   

Abstract

Rheumatoid arthritis (RA), although a systemic illness, is primarily a synovial disease. Morphologic and functional studies of immune cells within the synovium strongly suggest that disordered cellular immunity is key to the pathogenesis of RA. This article describes in detail the various cells found within the rheumatoid joint and compares them with those found in nonrheumatoid synovitis and in normal peripheral blood.

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Year:  1987        PMID： 3321208

Source DB:  PubMed          Journal:  Rheum Dis Clin North Am        ISSN： 0889-857X            Impact factor:   2.670


  11 in total

1.  Evidence for the presence of activated CD4 T cells with naive phenotype in the peripheral blood of patients with rheumatoid arthritis.

Authors:  D Maurer; T Felzmann; W Holter; P Petera; J Smolen; W Knapp
Journal:  Clin Exp Immunol       Date:  1992-03       Impact factor: 4.330

Review 2.  The role of cytokines in the pathogenesis of rheumatoid arthritis.

Authors:  P E Lipsky; L S Davis; J J Cush; N Oppenheimer-Marks
Journal:  Springer Semin Immunopathol       Date:  1989

3.  Anchorage-independent growth of synoviocytes from arthritic and normal joints. Stimulation by exogenous platelet-derived growth factor and inhibition by transforming growth factor-beta and retinoids.

Authors:  R Lafyatis; E F Remmers; A B Roberts; D E Yocum; M B Sporn; R L Wilder
Journal:  J Clin Invest       Date:  1989-04       Impact factor: 14.808

4.  Pannocytes: distinctive cells found in rheumatoid arthritis articular cartilage erosions.

Authors:  N J Zvaifler; V Tsai; S Alsalameh; J von Kempis; G S Firestein; M Lotz
Journal:  Am J Pathol       Date:  1997-03       Impact factor: 4.307

5.  Modulation of Th1 cytokines and inflammatory mediators by Euphorbia hirta in animal model of adjuvant-induced arthritis.

Authors:  Sheikh Fayaz Ahmad; Phalisteen Sultan; Abdelkader E Ashour; Tajdar Husain Khan; Sabry M Attia; Saleh A Bakheet; Adel R A Abd-Allah
Journal:  Inflammopharmacology       Date:  2012-12-11       Impact factor: 4.473

6.  Expression and functional significance of alternatively spliced CS1 fibronectin in rheumatoid arthritis microvasculature.

Authors:  M J Elices; V Tsai; D Strahl; A S Goel; V Tollefson; T Arrhenius; E A Wayner; F C Gaeta; J D Fikes; G S Firestein
Journal:  J Clin Invest       Date:  1994-01       Impact factor: 14.808

7.  Cytokines in chronic inflammatory arthritis. II. Granulocyte-macrophage colony-stimulating factor in rheumatoid synovial effusions.

Authors:  W D Xu; G S Firestein; R Taetle; K Kaushansky; N J Zvaifler
Journal:  J Clin Invest       Date:  1989-03       Impact factor: 14.808

8.  Cytokines in chronic inflammatory arthritis. IV. Granulocyte/macrophage colony-stimulating factor-mediated induction of class II MHC antigen on human monocytes: a possible role in rheumatoid arthritis.

Authors:  J M Alvaro-Gracia; N J Zvaifler; G S Firestein
Journal:  J Exp Med       Date:  1989-09-01       Impact factor: 14.307

9.  Local expression of matrix metalloproteinases, cathepsins, and their inhibitors during the development of murine antigen-induced arthritis.

Authors:  Uta Schurigt; Nadine Stopfel; Marion Hückel; Christina Pfirschke; Bernd Wiederanders; Rolf Bräuer
Journal:  Arthritis Res Ther       Date:  2004-12-10       Impact factor: 5.156

10.  Detection of serum soluble markers of immune activation in rheumatoid arthritis.

Authors:  T Kogure; T Itoh; Y Shimada; T Shintani; H Ochiai; K Terasawa
Journal:  Mediators Inflamm       Date:  1996       Impact factor: 4.711
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