| Literature DB >> 3321096 |
C R Pace-Asciak1, J M Martin, E J Corey.
Abstract
Evidence is presented to show that pancreatic islets of Langerhans are capable of producing hepoxilins A3 and B3 from endogenous substrates as well as 14C-labeled 12-HPETE. Both hepoxilins are active in stimulating the release of insulin from these cells in the presence of 10 mM glucose. These experiments suggest that the hepoxilins may participate as potential endogenous mediators of insulin release in islets of Langerhans.Entities:
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Year: 1986 PMID： 3321096 DOI： 10.1016/0163-7827(86)90127-x
Source DB: PubMed Journal: Prog Lipid Res ISSN： 0163-7827 Impact factor: 16.195