Literature DB >> 332090

Mycophenolic acid for psoriasis.

W S Lynch, H H Roenigk.   

Abstract

Mycophenolic acid is an antimetabolite used experimentally for the treatment of psoriasis. Thirty-eight patients were treated with mycophenolic acid. A double-blind, placebo-controlled study demonstrated the efficacy of mycophenolic acid (P less than .01). A long-term safety study showed the occurrence of hematologic abnormalities, viral infections, and carcinoma. The position of mycophenolic acid in the therapeutic treatment of psoriasis must await the results of a multicenter cooperative study.

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Year:  1977        PMID: 332090

Source DB:  PubMed          Journal:  Arch Dermatol        ISSN: 0003-987X


  4 in total

Review 1.  Preliminary risk-benefit assessment of mycophenolate mofetil in transplant rejection.

Authors:  W D Simmons; S C Rayhill; H W Sollinger
Journal:  Drug Saf       Date:  1997-08       Impact factor: 5.606

2.  In vitro effects of mycophenolic acid and allopurinol against Leishmania tropica in human macrophages.

Authors:  J D Berman; H K Webster
Journal:  Antimicrob Agents Chemother       Date:  1982-06       Impact factor: 5.191

Review 3.  Psoriasis therapy: a current perspective.

Authors:  N J Lowe
Journal:  West J Med       Date:  1983-08

4.  Synergistic Inhibition of Tumor Necrosis Factor-Alpha-Stimulated Pro-Inflammatory Cytokine Expression in HaCaT Cells by a Combination of Rapamycin and Mycophenolic Acid.

Authors:  Min Young Kim; Yun Young Lim; Hyeong Mi Kim; Young Min Park; Hoon Kang; Beom Joon Kim
Journal:  Ann Dermatol       Date:  2015-02-03       Impact factor: 1.444

  4 in total

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