Literature DB >> 332044

Determination of the anticonvulsant drug--dipropyl acetate (Epilim) in human plasma by gas chromatography.

H U-Schulz, P A Toseland.   

Abstract

A relatively simple gas chromatographic procedure is proposed for the analysis of the drug dipropylacetic acid in plasma. The compound is chromatographed, as the free acid after ether extraction. Prior to concentration of the solvent the acid is converted to its potassium salt, then regenerated to the free acid immediately before analysis.

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Year:  1977        PMID： 332044     DOI： 10.1177/000456327701400164

Source DB:  PubMed          Journal:  Ann Clin Biochem        ISSN： 0004-5632            Impact factor:   2.057


  5 in total

1.  Lack of hepatic enzyme inducing effect of sodium valproate.

Authors:  J Oxley; A Hedges; K A Makki; A Monks; A Richens
Journal:  Br J Clin Pharmacol       Date:  1979-08       Impact factor: 4.335

2.  Disposition of sodium valproate in epileptic patients.

Authors:  E Perucca; G Gatti; G M Frigo; A Crema; S Calzetti; D Visintini
Journal:  Br J Clin Pharmacol       Date:  1978-06       Impact factor: 4.335

3.  Decreased plasma protein binding of phenytoin in patients on valproic acid.

Authors:  R Dahlqvist; O Borgå; A Rane; Z Walsh; F Sjöqvist
Journal:  Br J Clin Pharmacol       Date:  1979-12       Impact factor: 4.335

4.  Modification of phenytoin clearance by valproic acid in normal subjects.

Authors:  G M Frigo; S Lecchini; G Gatti; E Perucca; A Crema
Journal:  Br J Clin Pharmacol       Date:  1979-12       Impact factor: 4.335

5.  Valproic acid and diazepam interaction in vivo.

Authors:  S Dhillon; A Richens
Journal:  Br J Clin Pharmacol       Date:  1982-04       Impact factor: 4.335
  5 in total

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