Literature DB >> 33199393

Potential Mobilization of mcr-10 by an Integrative Mobile Element via Site-Specific Recombination in Cronobacter sakazakii.

Jing Yang1,2,3, Lina Liu4, Yu Feng1,3,4, Da He1,3, Chengcheng Wang1,3,4, Zhiyong Zong5,3,4,6.   

Abstract

mcr-10 is a newly identified plasmid-borne colistin resistance gene, but its mobilization mechanism remains unclear. In this study, mcr-10 was found on an IncFIB plasmid carrying virulence genes mrkABCDFJ, iucABCD/iutA, and eitCBAD in a Cronobacter sakazakii isolate. By comparison with closely related plasmids, two recombination sites were identified flanking the genetic element containing mcr-10 and an integrase-encoding gene, suggesting that site-specific recombination mediated by an integrase of an integrative mobile element is a potential mechanism for mobilizing mcr-10.
Copyright © 2021 American Society for Microbiology.

Entities:  

Keywords:  Cronobacter sakazakii; colistin; colistin resistance; integrase; mcr; mcr-10; site-specific recombination

Mesh：

Substances：

Year:  2021        PMID： 33199393      PMCID： PMC7849017          DOI： 10.1128/AAC.01717-20

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  18 in total

1.  SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing.

Authors:  Anton Bankevich; Sergey Nurk; Dmitry Antipov; Alexey A Gurevich; Mikhail Dvorkin; Alexander S Kulikov; Valery M Lesin; Sergey I Nikolenko; Son Pham; Andrey D Prjibelski; Alexey V Pyshkin; Alexander V Sirotkin; Nikolay Vyahhi; Glenn Tesler; Max A Alekseyev; Pavel A Pevzner
Journal:  J Comput Biol       Date:  2012-04-16       Impact factor: 1.479

2.  Characterization of putative virulence genes on the related RepFIB plasmids harbored by Cronobacter spp.

Authors:  A A Franco; L Hu; C J Grim; G Gopinath; V Sathyamoorthy; K G Jarvis; C Lee; J Sadowski; J Kim; M H Kothary; B A McCardell; B D Tall
Journal:  Appl Environ Microbiol       Date:  2011-03-18       Impact factor: 4.792

3.  Presence of AmpC beta-lactamases, CSA-1, CSA-2, CMA-1, and CMA-2 conferring an unusual resistance phenotype in Cronobacter sakazakii and Cronobacter malonaticus.

Authors:  Andrea Müller; Herbert Hächler; Roger Stephan; Angelika Lehner
Journal:  Microb Drug Resist       Date:  2014-02-25       Impact factor: 3.431

Review 4.  Towards Understanding MCR-like Colistin Resistance.

Authors:  Jian Sun; Huimin Zhang; Ya-Hong Liu; Youjun Feng
Journal:  Trends Microbiol       Date:  2018-03-07       Impact factor: 17.079

5.  MrkH, a novel c-di-GMP-dependent transcriptional activator, controls Klebsiella pneumoniae biofilm formation by regulating type 3 fimbriae expression.

Authors:  Jonathan J Wilksch; Ji Yang; Abigail Clements; Jacinta L Gabbe; Kirsty R Short; Hanwei Cao; Rosalia Cavaliere; Catherine E James; Cynthia B Whitchurch; Mark A Schembri; Mary L C Chuah; Zhao-Xun Liang; Odilia L Wijburg; Adam W Jenney; Trevor Lithgow; Richard A Strugnell
Journal:  PLoS Pathog       Date:  2011-08-25       Impact factor: 6.823

6.  Insertion Sequence IS26 Reorganizes Plasmids in Clinically Isolated Multidrug-Resistant Bacteria by Replicative Transposition.

Authors:  Susu He; Alison Burgess Hickman; Alessandro M Varani; Patricia Siguier; Michael Chandler; John P Dekker; Fred Dyda
Journal:  MBio       Date:  2015-06-09       Impact factor: 7.867

7.  Cronobacter, the emergent bacterial pathogen Enterobacter sakazakii comes of age; MLST and whole genome sequence analysis.

Authors:  Stephen J Forsythe; Benjamin Dickins; Keith A Jolley
Journal:  BMC Genomics       Date:  2014-12-16       Impact factor: 3.969

8.  Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads.

Authors:  Ryan R Wick; Louise M Judd; Claire L Gorrie; Kathryn E Holt
Journal:  PLoS Comput Biol       Date:  2017-06-08       Impact factor: 4.475

9.  Antibiotic and Desiccation Resistance of Cronobacter sakazakii and C. malonaticus Isolates from Powdered Infant Formula and Processing Environments.

Authors:  Peng Fei; Yujun Jiang; Jing Feng; Stephen J Forsythe; Ran Li; Yanhong Zhou; Chaoxin Man
Journal:  Front Microbiol       Date:  2017-03-02       Impact factor: 5.640

10.  Identification of novel mobile colistin resistance gene mcr-10.

Authors:  Chengcheng Wang; Yu Feng; Lina Liu; Li Wei; Mei Kang; Zhiyong Zong
Journal:  Emerg Microbes Infect       Date:  2020-03-02       Impact factor: 7.163
View more
  4 in total

1.  Emergence of Colistin Resistance Gene mcr-10 in Enterobacterales Isolates Recovered from Fecal Samples of Chickens, Slaughterhouse Workers, and a Nearby Resident.

Authors:  Linna Xu; Fen Wan; Hao Fu; Biao Tang; Zhi Ruan; Yonghong Xiao; Qixia Luo
Journal:  Microbiol Spectr       Date:  2022-04-12

2.  Identification of Mobile Colistin Resistance Gene mcr-10 in Disinfectant and Antibiotic Resistant Escherichia coli from Disinfected Tableware.

Authors:  Senlin Zhang; Honghu Sun; Guangjie Lao; Zhiwei Zhou; Zhuochong Liu; Jiong Cai; Qun Sun
Journal:  Antibiotics (Basel)       Date:  2022-07-01

Review 3.  Global epidemiology, genetic environment, risk factors and therapeutic prospects of mcr genes: A current and emerging update.

Authors:  Masego Mmatli; Nontombi Marylucy Mbelle; John Osei Sekyere
Journal:  Front Cell Infect Microbiol       Date:  2022-08-26       Impact factor: 6.073

4.  Characterization of Cronobacter sakazakii Strains Originating from Plant-Origin Foods Using Comparative Genomic Analyses and Zebrafish Infectivity Studies.

Authors:  Hyein Jang; Athmanya Eshwar; Angelika Lehner; Jayanthi Gangiredla; Isha R Patel; Junia Jean-Gilles Beaubrun; Hannah R Chase; Flavia Negrete; Samantha Finkelstein; Leah M Weinstein; Katie Ko; Nicole Addy; Laura Ewing; Jungha Woo; Youyoung Lee; Kunho Seo; Ziad Jaradat; Shabarinath Srikumar; Séamus Fanning; Roger Stephan; Ben D Tall; Gopal R Gopinath
Journal:  Microorganisms       Date:  2022-07-11
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.