Literature DB >> 33196863

Impaired left atrial mechanical functions as indicators for increased aortic root diameter in hypertensive and diabetic patients.

Ezgi Kalaycıoğlu1, Mustafa Çetin2, Ali Gökhan Özyıldız3, Tuncay Kırış4.   

Abstract

OBJECTIVES: Previous studies have demonstrated that increased aortic root diameter (ARD) is frequently associated with increased cardiovascular (CV) events and is a predictor of stroke. Two-dimensional speckle tracking echocardiography (2D-STE) provides a better evaluation of left atrial (LA) functions. Left atrial mechanical dispersion is a useful predictor of new-onset atrial fibrillation (AF) independent of LA enlargement and dysfunction. We aimed to investigate the relationship between ARD and LA mechanical functions.
METHODS: The present study included 93 consecutive patients with hypertension and diabetes. The relationships between ARD and LA functions was evaluated.
RESULTS: Study population was divided into two groups according to the mean ARD values: group 1 (ARD ≤30.03 mm, n = 53) and group 2 (ARD >30.03 mm, n = 40). In group 2, age, LA max volume (vol), LA pre A vol, LA min vol, LA emptying fraction, LA active ejection fraction (EF), and LA expansion index were significantly higher compared to group 1. S‑LAs and SR-LAs (peak LA strain and strain rate, respectively, during ventricular systole) and S‑LAe and SR-LAe (peak early diastolic LA strain and strain rate, respectively) were significantly lower in group 2 compared to group 1. Age, LA max vol, LA pre A vol, LA min vol, LA emptying fraction, LA active EF, LA expansion index, S‑LAs, S‑LAe, SR-LAs, and SR-LAe were significantly associated with increased ARD. In multivariate logistic regression analysis, age, LA expansion index, and SR-LAe were independent predictors for ARD.
CONCLUSION: Impaired LA mechanical functions determined by speckle tracking methods are related with increased ARD independent of LV diastolic dysfunction.
© 2020. Springer Medizin Verlag GmbH, ein Teil von Springer Nature.

Entities:  

Keywords:  Atrial fibrillation; Hypertension; Left atrium; Stroke; Two-dimensional speckle tracking echocardiography

Mesh:

Year:  2020        PMID: 33196863     DOI: 10.1007/s00059-020-04997-x

Source DB:  PubMed          Journal:  Herz        ISSN: 0340-9937            Impact factor:   1.443


  3 in total

Review 1.  American Society of Echocardiography recommendations for use of echocardiography in clinical trials.

Authors:  John S Gottdiener; James Bednarz; Richard Devereux; Julius Gardin; Allan Klein; Warren J Manning; Annitta Morehead; Dalane Kitzman; Jae Oh; Miguel Quinones; Nelson B Schiller; James H Stein; Neil J Weissman
Journal:  J Am Soc Echocardiogr       Date:  2004-10       Impact factor: 5.251

Review 2.  The role of myocardial wall thickness in atrial arrhythmogenesis.

Authors:  John Whitaker; Ronak Rajani; Henry Chubb; Mark Gabrawi; Marta Varela; Matthew Wright; Steven Niederer; Mark D O'Neill
Journal:  Europace       Date:  2016-05-31       Impact factor: 5.214

3.  Endothelial dysfunction, subclinical atherosclerosis and LDL cholesterol are the independent predictors of left atrial functions in hypertension.

Authors:  Mustafa Çetin; Turan Erdoğan; Tuncay Kırış; Ali Gökhan Özyıldız; Elif Ergül; Emre Durakoğlugil; Hüseyin Durak; Ezgi Kalaycıoğlu; Yüksel Çiçek
Journal:  Int J Cardiovasc Imaging       Date:  2019-10-04       Impact factor: 2.357

  3 in total

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