Literature DB >> 33194501

Unfortunate Outcomes in Patients With SARS-CoV-2 Superimposed on Pneumococcal Pneumonia.

Sherif Elkattawy1, Ramez Alyacoub1, Ahmed Mowafy2, Islam Younes2, Carlos Remolina3.   

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the disease it causes, coronavirus disease 2019 (COVID-19), continue to have socioeconomic as well as health implications worldwide. The virus has already led to over 200,000 deaths in the United States alone. This is most likely secondary to quick respiratory deterioration seen in patients inflicted with the virus. In other words, the heightened inflammatory response leads to major organ system damage, which leads to rapid decompensation of the patient's clinical condition. Interestingly enough, some patients present with both the novel virus as well as a superimposed bacterial infection that further complicates the management of the disease. We present a case of a patient with a positive polymerase chain reaction (PCR) test for SARS-CoV-2 as well as a pneumococcal urine antigen; he was treated with both appropriate antibiotics as well as dexamethasone and remdesivir for pneumonia and novel virus, respectively. The patient's hypoxemia continued to worsen with appropriate means of oxygenation and eventually led to cardiac arrest.
Copyright © 2020, Elkattawy et al.

Entities:  

Keywords:  covid-19 outbreak; pneumococcal antigen

Year:  2020        PMID: 33194501      PMCID: PMC7660127          DOI: 10.7759/cureus.10939

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  6 in total

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Authors:  Carlos M Luna; Laura Pulido; Diego Burgos
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Review 2.  Bench-to-bedside review: bacterial pneumonia with influenza - pathogenesis and clinical implications.

Authors:  Koenraad F van der Sluijs; Tom van der Poll; René Lutter; Nicole P Juffermans; Marcus J Schultz
Journal:  Crit Care       Date:  2010-04-19       Impact factor: 9.097

3.  Recognition and management of respiratory co-infection and secondary bacterial pneumonia in patients with COVID-19.

Authors:  Chao-Ping Wu; Fatima Adhi; Kristin Highland
Journal:  Cleve Clin J Med       Date:  2020-11-02       Impact factor: 2.321

4.  Pneumococcal superinfection in COVID-19 patients: A series of 5 cases.

Authors:  David Cucchiari; Juan M Pericàs; Josep Riera; Roberto Gumucio; Emmanuel Coloma Md; David Nicolás
Journal:  Med Clin (Barc)       Date:  2020-06-05       Impact factor: 1.725

Review 5.  Bacterial co-infection and secondary infection in patients with COVID-19: a living rapid review and meta-analysis.

Authors:  Bradley J Langford; Miranda So; Sumit Raybardhan; Valerie Leung; Duncan Westwood; Derek R MacFadden; Jean-Paul R Soucy; Nick Daneman
Journal:  Clin Microbiol Infect       Date:  2020-07-22       Impact factor: 8.067

Review 6.  Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID-19) implicate special control measures.

Authors:  Yixuan Wang; Yuyi Wang; Yan Chen; Qingsong Qin
Journal:  J Med Virol       Date:  2020-03-29       Impact factor: 20.693

  6 in total
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1.  The Spectrum of Antibiotic Prescribing During COVID-19 Pandemic: A Systematic Literature Review.

Authors:  Sara H Al-Hadidi; Hashim Alhussain; Hamad Abdel Hadi; Alreem Johar; Hadi M Yassine; Asmaa A Al Thani; Nahla O Eltai
Journal:  Microb Drug Resist       Date:  2021-06-01       Impact factor: 3.431

  1 in total

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