| Literature DB >> 33193462 |
Qiong Zhou1, Virginia Chen2, Casey P Shannon2, Xiao-Shan Wei1, Xuan Xiang1, Xu Wang1, Zi-Hao Wang1, Scott J Tebbutt2,3, Tobias R Kollmann4, Eleanor N Fish5.
Abstract
[This corrects the article DOI: 10.3389/fimmu.2020.01061.].Entities:
Keywords: ARDS; COVID-19; IL-6; inflammation; interferon; viral shedding
Year: 2020 PMID: 33193462 PMCID: PMC7653513 DOI: 10.3389/fimmu.2020.615275
Source DB: PubMed Journal: Front Immunol ISSN: 1664-3224 Impact factor: 7.561
Demographics and clinical characteristics of patient cohort.
| IFN n = 7 | IFN+ARB n = 46 | ARBn = 24 | p-value | |
|---|---|---|---|---|
| Age, yrs | 41.3 (27–68) | 40.4 (25–80) | 64.5 (37–73) | <0.001 |
| Male (%) | 0 (0.0%) | 20 (43.5%) | 11 (45.8%) | 0.076 |
| Comorbidities (%) | 14.3% | 15.2% | 54.2% | 0.002 |
|
| ||||
| Fever (%) | 57.1% | 58.7% | 70.8% | 0.632 |
| Cough (%) | 42.9% | 50.0% | 54.2% | 0.888 |
| Fatigue (%) | 14.3% | 23.9% | 37.5% | 0.422 |
| Myalgia (%) | 14.3% | 13.0% | 29.2% | 0.228 |
| Headache (%) | 14.3% | 6.52% | 4.17% | 0.590 |
| Pharyngalgia (%) | 0.00% | 13.0% | 8.33% | 0.742 |
| Chest pain (%) | 14.3% | 6.52% | 20.8% | 0.134 |
| Expectoration (%) | 14.3% | 8.70% | 20.8% | 0.281 |
| Nausea (%) | 0.00% | 0.00% | 4.17% | 0.403 |
| Diarrhea (%) | 14.3% | 4.35% | 20.8% | 0.081 |
| Days from symptom onset to hospital admission | 8.0 | 6.5 | 10.0 | 0.087 |
| Days from symptom onset to 1st treatment | 8.0 | 8.0 | 17.0 | <0.001 |
Hypertension, diabetes, COPD, chronic bronchitis, heart disease, cancer.
Median and interquartile range [Q1, Q3] are reported.